Results 101 to 110 of about 1,188,877 (313)
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
, 2015 Delays and deficits in structural language and social communication are common features of autism spectrum disorder (ASD), but the exact nature of these problems is unclear.
Best, Catherine T. (R11322) +1 more
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Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Molecular Oncology, EarlyView.Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source
Optimal Pricing for Service Provisioning in the Secondary Spectrum Market
MATEC Web of Conferences, 2018 In this paper, we investigate the problem of spectrum sharing in a secondary spectrum market where one secondary operator provisions network access services to a number of secondary users (SUs) by leasing spectrum from spectrum holder.
Gu Fan +4 more
doaj +1 more source
TVWS policies to enable efficient spectrum sharing [PDF]
The transition from analogue to the Digital Terrestrial Television (DTV) in Europe is planned to be completed by the end of the year 2012. The DTV spectrum allocation is such that there are a number of TV channels which cannot be used for additional high
Dosch, Christoph +2 more
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Ken Wilber's Spectrum Model: Identifying Alternative Soteriological Perspectives [PDF]
, 2001 I identify two problematic strands of Wilber's transpersonal theory. First, I question Wilber's claim that his spectrum model is supported by the materials of all the world's major mystical traditions.
Schlamm, Leon
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Molecular Oncology, EarlyView.Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source
The spectrum of the force-based quasicontinuum operator for a homogeneous periodic chain [PDF]
, 2012 We show under general conditions that the linearized force-based quasicontinuum (QCF) operator has a real, positive spectrum. The spectrum is identical to that of the quasinonlocal quasicontinuum (QNL) operator in the case of second-neighbor interactions.
Ortner, C. +4 more
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Molecular Oncology, EarlyView.EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain +10 more
wiley +1 more source
A note on two expressions for the spatial power spectrum of the geomagnetic field
Annals of Geophysics, 1996 The spatial power spectrum of the geomagnetic field is usually assumed to be exponential in the spherical harmonic degree (n). An equally valid assumption, however, is that the spectrum at the surface of the Earth's core has a power-law dependence on n ...
D. R. Barraclough, A. De Santis
doaj +1 more source