Results 81 to 90 of about 1,188,877 (313)

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

Spectrum of Discrete Second-Order Difference Operator with Sign-Changing Weight and Its Applications

open access: yesDiscrete Dynamics in Nature and Society, 2014
Let T>1 be an integer, and let𝕋=1,2,…,T. We discuss the spectrum of discrete linear second-order eigenvalue problems Δ2ut-1+λmtut=0, t∈𝕋,  u0=uT+1=0, where λ≠0 is a parameter, m:𝕋→ℝ changes sign and mt≠0 on 𝕋.
Ruyun Ma, Chenghua Gao
doaj   +1 more source

Are autistic traits measured equivalently in individuals with and without an Autism Spectrum Disorder?:An invariance analysis of the Autism Spectrum Quotient Short Form

open access: yes, 2014
It is common to administer measures of autistic traits to those without autism spectrum disorders (ASDs) with, for example, the aim of understanding autistic personality characteristics in non-autistic individuals. Little research has examined the extent
Booth, Thomas   +6 more
core   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

On some fučík type problem with cubic nonlinearity

open access: yesMathematical Modelling and Analysis, 2011
We study the second order Fučík type problem with cubic nonlinearity  and construct the Fučík spectrum for this problem. The spectrum obtained under normalization condition (otherwise problem may have continuous spectra) structurally is similar to Fučík ...
N. Sergejeva
doaj   +1 more source

Essays on optimal spectrum management for expanding wireless communications [PDF]

open access: yes
Wireless communications are experiencing an unprecedented expansion. The increasing mobility of the communication society and the pace of technological change are growing pressure for more spectrum to support more users, more uses and more capacity ...
Minervini, Leo Fulvio
core  

Mixed‐class J‐domain protein scaffolds promote expanded aggregate handling and multivalent Hsp70 engagement during functional disaggregase assembly

open access: yesFEBS Letters, EarlyView.
Protein aggregates threaten proteostasis and cell health. In human cells, Hsp70–J‐domain protein‐based disaggregases remove aggregates, but how they assemble remains unclear. Our biochemical findings show that DNAJA2‐ and DNAJB1‐containing disaggregase scaffolds enhance luciferase aggregate targeting, and that Hsp70 recruitment by both J‐domain ...
Anna Szlachcic, Nadinath B. Nillegoda
wiley   +1 more source

Collusive Bidding: Lessons from the FCC Spectrum Auctions [PDF]

open access: yes
The Federal Communications Commission (FCC) spectrum auctions use a simultaneous ascending auction design. Bidders bid on numerous communication licenses simultaneously, with bidding remaining open on all licenses until no bidder is willing to bid higher
Jesse Schwartz, Peter Cramton
core  

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

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