Results 61 to 70 of about 359,195 (267)

The Effectiveness of Positive Psychotherapy on Improving Psychological Adjustment of the Students with Suicidal Ideation: With an Emphasis on Religious Teachings

مسائل کاربردی تعلیم و تربیت اسلامی, 2020
Adolescence, one of the most critical periods of development, leads to various stressors. Incompatibility with this period may cause injuries such as suicidal ideation.
Pari Maleki Ghalandoz, Bagher sardary
doaj  

The G-protein Coupled Receptor GPR8 Regulates Secondary Metabolism in Trichoderma reesei

Frontiers in Bioengineering and Biotechnology, 2020
Changing environmental conditions are of utmost importance for regulation of secondary metabolism in fungi. Different environmental cues including the carbon source, light and the presence of a mating partner can lead to altered production of compounds ...
Wolfgang Hinterdobler, Sabrina Beier, Alberto Alonso Monroy, Harald Berger, Christoph Dattenböck, Monika Schmoll   +5 more
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Primary-Secondary School Transition: Impacts and Opportunities for Adjustment

, 2021
The transition from primary to secondary education is an important period in children’s lives: academically, socially and emotionally, and can be particularly challenging for some children. Occurring alongside puberty and a change in focus from parents to peer relationships, the transition can be a difficult adjustment for some to navigate.
Harris, Joanne, Nowland, Rebecca
openaire   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Effect of Cultural Intelligence on the Work Adjustment of PE Teachers in Primary and Secondary Schools in a Large City in Iran

Physical Culture and Sport: Studies and Research, 2016
This study aimed to measure the cultural intelligence of physical education (PE) teachers’ work adjustment in primary and secondary schools in a large city in Iran (Isfahan).
Mirsafian Hamidreza
doaj   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

Persuasive Arguments and Career Decisions Among Grade 12 Learners in Selected Secondary Schools in South Africa

Studia Universitatis Babeş-Bolyai. Psychologia-Paedagogia
The study examined persuasive arguments and adjustment in career decisions among grade 12 learners in selected secondary schools in South Africa. Persuasive Arguments theory guided the research.
Peter JO ALOKA
doaj   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Impact of beta-lactam antibiotic renal dose adjustment on clinical outcomes in patients with septic shock and acute kidney injury from gram-negative bloodstream infections: a multicenter observational study

CMI Communications
Objective: Beta-lactam antibiotics are the backbone of therapy for critically ill patients with sepsis; however, these patients experience pharmacokinetic changes that alter beta-lactam exposure.
Melissa L. Thompson Bastin, Megan A Rech, Kevin D. Betthauser, Mojdeh S. Heavner, Michelle Horng, Steven M. Lemieux, Mollie Lumpkin, Erin K. McCreary, Michael A. Ruggero, Patrick M. Wieruszewski, Y. Vivian Tsai, Jose Barro, Bhavna Jois, James Mease, Carly Cheng, Emily L. Heil   +15 more
doaj   +1 more source