Results 161 to 170 of about 8,095,731 (348)

Archiving Longitudinal Data for Future Research. Why Qualitative Data Add to a Study's Usefulness

Forum: Qualitative Social Research, 2000
In this paper we discuss the special challenges that data archives face when archiving and preparing for new research longitudinal studies with a large qualitative component.
Jacquelyn B. James, Annemette Sørensen
doaj  

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

Molecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen, Kristiane Søreng, Chiara Veroni, Laura Trachsel‐Moncho, Nagham Asp, Robin Gaupset, Lars Gustav Lyckander, Helene Knævelsrud, Lars Eftang, Anne Simonsen   +9 more
wiley   +1 more source

Exploring Barriers to Recovery Amongst Women with Psychosis: A Qualitative Secondary Analysis. [PDF]

Cult Med Psychiatry
Lock C, Lavis A, Pendrous R, Greenfield S.   +3 more
europepmc   +1 more source

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

Molecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata, Koji Ando, Hirofumi Hasuda, Koshi Mimori, Elizabeth C. Unan, Siddhartha Pulukuri, Aahana Tiku, Allison Berger, Eiji Oki, Ajit Bharti, Tomoharu Yoshizumi   +10 more
wiley   +1 more source

Secondary Analysis of the Japanese National Character Survey : Focusing on Question Items of Religious Consciousness [PDF]

, 2019
一史 真鍋, Kazufumi Manabe
openalex  

Molecular cancer prevention: Intercepting disease

Molecular Oncology, EarlyView.
Oncological practice must evolve, from treating established tumours to proactive cancer interception before clinical manifestation. This will require mechanistic insight into tumour initiation, validated biomarkers of early disease development and redesigned clinical trials, enabling cancer interception to become a core pillar of oncology with the ...
Charlotte Grieco, Tej Pandya, Charles Swanton   +2 more
wiley   +1 more source

Consanguineous Marriages and Their Association With Women’s Reproductive Health and Fertility Behavior in Pakistan: Secondary Data Analysis From Demographic and Health Surveys, 1990–2018 [PDF]

, 2020
Sarosh Iqbal, Rubeena Zakar, Florian Fischer, Muhammad Zakria Zakar   +3 more
openalex   +1 more source

Child's Temperament as Risk Factor for Preoperative Anxiety-A Secondary Analysis of the ALPAKA Trial. [PDF]

Paediatr Anaesth
Jacobi T, Walter S, Pickartz A, Baller G, Becher T, Lautenschläger I, Sablewski A.   +6 more
europepmc   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

Data record for the secondary endpoint analysis of regulatory T cell phenotypes from the "Adaptive study of IL-2 dose on regulatory T cells in Type 1 Diabetes (DILT1D)"

, 2017
Frank Waldron-Lynch
openalex   +1 more source