Results 141 to 150 of about 82,003 (259)

Flanking‐Group Engineering Unlocks Emerging Functionalities in Diketopyrrolopyrrole Semiconductors

open access: yesAdvanced Science, EarlyView.
This review presents a comprehensive and unified perspective of flanking‐group engineering in Diketopyrrolopyrrole (DPP) based organic semiconductors that connects molecular‐level design with cross‐device functionalities. By integrating insights from molecular design, solid‐state packing, and device physics, this review seeks to establish general ...
Xiaoyun Wu   +5 more
wiley   +1 more source

Cediranib with weekly paclitaxel or olaparib versus weekly paclitaxel for advanced or recurrent endometrial cancer (COPELIA): a multicentre, open-label, randomised, phase 2 trial in the UK. [PDF]

open access: yesEClinicalMedicine
Morgan RD   +44 more
europepmc   +1 more source

PEAR1 Promotes Glucose Metabolism Reprogramming in Sepsis‐Associated Acute Lung Injury via AARS1‐Mediated HIF‐1α Lactylation

open access: yesAdvanced Science, EarlyView.
This study revealed that a PEAR1/HIF‐1α/ glycolysis/lactate/H3K18la positive feedback loop in PMVECs that drives the development of S‐ALI. Mechanistically, PEAR1 mediates the binding of HIF‐1α to AARS1, leading to the lactylation of HIF‐1α, the primary lactylation site of which is K172.
Shuai Li   +15 more
wiley   +1 more source

Systemic Nanomechanical Single‐Cell Profiling Reveals Mechanophenotype Transitions Under Therapeutic Perturbation

open access: yesAdvanced Science, EarlyView.
Single‐cell mechanomics demonstrates that pharmacological perturbation changes cytoskeletal and cortical structure, suppressing cancer cell invasiveness. By integrating atomic force microscopy (AFM)‐based cortical measurements with stimulated emission depletion (STED)‐resolved adhesion and cytoskeletal organization, this approach identifies nanoscale ...
Minhee Ku   +4 more
wiley   +1 more source

Iptacopan monotherapy resulted in increased hemoglobin level in patients with PNH and hemoglobin ≥10 g/dL after anti-C5 therapy. [PDF]

open access: yesHemasphere
Kulasekararaj A   +31 more
europepmc   +1 more source

A Molten Salt Extraction Method for Palladium Recovery via the CaPd2 Intermetallic Compound

open access: yesAdvanced Science, EarlyView.
A designed Ca → CaPd2 → Pd pathway enables acid–free palladium recovery in molten salt. Calcium alloying forms anionic CaPd2, which is selectively oxidized by iodine from CaI2 to yield high–purity metallic Pd. ABSTRACT To address palladium scarcity and the low efficiency of conventional recovery processes, this work presents a molten–salt extraction ...
Jiapeng Zhang   +6 more
wiley   +1 more source

Visceral leishmaniasis risk clusters on Brazil's borders: 2013 to 2022. [PDF]

open access: yesRev Soc Bras Med Trop
Moreira WDC   +6 more
europepmc   +1 more source

Bio‐Inspired Bidirectional Winding Origami With Programmable Modular Reconfigurability and Scalability

open access: yesAdvanced Science, EarlyView.
A bio‐inspired bidirectional‐winding origami platform enables scalable and programmable deployable structures. Double axial folding inspired by earwig hindwings and Flasher‐based hybridization create modular multilayer architectures with diverse attainable winding angles under fixed boundary conditions.
Wenyao Zhang   +5 more
wiley   +1 more source

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