Results 31 to 40 of about 3,308,443 (254)

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola   +11 more
wiley   +1 more source

ARC-Publicaties 35

open access: yes, 1999
Aanvullende archeologische inventarisaties enonderzoek in 1999: Groningen, Dronrijp, Ferwert, Sneek, Drouwen, Dwingeloo, Groloo, Norg, Ruinen, Valthe, Zuidlaren, Goor en ...
ARC bv
core   +1 more source

ARC Computing Element System Administrator Guide [PDF]

open access: yes, 2013
The ARC Computing Element (CE) is an EMI product allowing submission and management of applications running on DCI computational ...
Ould-Saada, Farid
core   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

open access: yesMolecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur   +11 more
wiley   +1 more source

Influence of Different Compensation Modes on Morphological and Electrical Characteristics of Secondary Arcs

open access: yesCSEE Journal of Power and Energy Systems
UHV transmission lines are usually equipped with high-voltage shunt reactors. These reactors and the resulting degree of compensation affect the voltage, current, and other electrical characteristics of secondary arcs.
Hongshun Liu   +5 more
doaj   +1 more source

ARC-Publicaties 80

open access: yes, 2003
Bundel van klein regionaal onderzoek ...
ARC bv
core   +1 more source

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

open access: yesMolecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez   +5 more
wiley   +1 more source

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

open access: yesMolecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault   +12 more
wiley   +1 more source

ARC-Publicaties 121

open access: yes, 2005
Op het zuidwestelijke gedeelte van het Husselerveld te Putten (Gld.) is door de gemeente Putten nieuwbouw in de vorm van huizen gepland. De werkzaamheden voor het bouwrijp maken van het plangebied zullen het eventueel aanwezige bodemarchief vernietigen ...
Waveren, A.M.I., Blom, M.C.
core   +1 more source

Characterization of therapeutic antibodies targeting lymphatic and vascular resistance factor for the treatment of hypervascularized and highly metastatic cancers

open access: yesMolecular Oncology, EarlyView.
LVRF (lymphatic and vascular resistance factor) is a VEGFA splice variant upregulated in response to anti‐angiogenic therapy that fosters tumor adaptation through enhanced vascularization, lymphangiogenesis, and metastatic dissemination. Targeting LVRF with fully human neutralizing antibodies disrupts these processes and limits resistant tumor growth ...
Marion David   +12 more
wiley   +1 more source

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