Results 31 to 40 of about 3,308,443 (254)
Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source
Aanvullende archeologische inventarisaties enonderzoek in 1999: Groningen, Dronrijp, Ferwert, Sneek, Drouwen, Dwingeloo, Groloo, Norg, Ruinen, Valthe, Zuidlaren, Goor en ...
ARC bv
core +1 more source
ARC Computing Element System Administrator Guide [PDF]
The ARC Computing Element (CE) is an EMI product allowing submission and management of applications running on DCI computational ...
Ould-Saada, Farid
core +1 more source
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur +11 more
wiley +1 more source
UHV transmission lines are usually equipped with high-voltage shunt reactors. These reactors and the resulting degree of compensation affect the voltage, current, and other electrical characteristics of secondary arcs.
Hongshun Liu +5 more
doaj +1 more source
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez +5 more
wiley +1 more source
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault +12 more
wiley +1 more source
Op het zuidwestelijke gedeelte van het Husselerveld te Putten (Gld.) is door de gemeente Putten nieuwbouw in de vorm van huizen gepland. De werkzaamheden voor het bouwrijp maken van het plangebied zullen het eventueel aanwezige bodemarchief vernietigen ...
Waveren, A.M.I., Blom, M.C.
core +1 more source
LVRF (lymphatic and vascular resistance factor) is a VEGFA splice variant upregulated in response to anti‐angiogenic therapy that fosters tumor adaptation through enhanced vascularization, lymphangiogenesis, and metastatic dissemination. Targeting LVRF with fully human neutralizing antibodies disrupts these processes and limits resistant tumor growth ...
Marion David +12 more
wiley +1 more source

