Results 41 to 50 of about 4,045,011 (313)

The use of simulation to address the acute care skills deficit in pre-registration nursing students: A clinical skills perspective [PDF]

open access: yes, 2011
The increase in patient acuity in primary and secondary settings is continuing, with a corresponding increase in the need for technological competence in these areas.
Nickless, Lesley
core   +1 more source

Evaluating the Utility of Paired Tumor and Germline Targeted DNA Sequencing for Pediatric Oncology Patients: A Single Institution Report

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate the diagnostic yield and utility of universal paired tumor–normal multigene panel sequencing in newly diagnosed pediatric solid and central nervous system (CNS) tumor patients and to compare the detection of germline pathogenic/likely pathogenic variants (PV/LPVs) against established clinical referral criteria for cancer ...
Natalie Waligorski   +9 more
wiley   +1 more source

Challenges of managing people with multimorbidity in today’s healthcare systems [PDF]

open access: yes, 2015
Multimorbidity is a growing issue and poses a major challenge to health care systems around the world. Multimorbidity is related to ageing but many studies have now shown that it is also socially patterned, being more common and occurring at an earlier ...
Mercer, Stewart, Moffat, Keith
core   +3 more sources

Primary and secondary care collaboration for end of life care [PDF]

open access: yesLondon Journal of Primary Care, 2009
Background The NHS does not deliver the care that people want at the end of life and receives large numbers of complaints about care in hospitals. This is a symptom of a wider problem which leads to over-hospitalisation of elderly people. This was demonstrated clearly in a hospital utilisation study in a south London borough which showed that over 40 ...
openaire   +2 more sources

Preferences of Pediatric Patients and Their Caregivers for Chemotherapy‐Induced Nausea and Vomiting Control Endpoints: A Mixed Methods Study

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Purpose Although not always achieved, complete chemotherapy‐induced nausea and vomiting (CINV) control is the conventional goal of CINV prophylaxis. In this two‐center, mixed‐methods study, we sought to understand the preferences of adolescent patients and family caregivers for CINV control endpoints.
Haley Newman   +8 more
wiley   +1 more source

The research activities of Ontario’s large community acute care hospitals: a scoping review

open access: yesBMC Health Services Research, 2017
Background Ontario’s large community hospitals (LCHs) provide care to 65% of the province’s hospitalized patients, yet we know very little about their research activities.
Giulio DiDiodato   +2 more
doaj   +1 more source

Research on patients with multiple health conditions: different constructs, different views, one voice [PDF]

open access: yes, 2011
Technological advances, improvements in medical care and public health policies have resulted in a growing proportion of patients with multiple health conditions.
Fortin, M., Mercer, S.W., Valderas, J.M.
core   +3 more sources

Intravitreal GD2‐Specific Chimeric Antigen Receptor T‐Cell Therapy for Refractory Retinoblastoma

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Effective treatments for advanced, treatment‐resistant retinoblastoma (RB) remain limited. GD2‐specific chimeric antigen receptor (CAR) T cells show potent antitumor activity with minimal toxicity but have not previously been evaluated in RB.
Subongkoch Subhadhirasakul   +13 more
wiley   +1 more source

Characterising generalism in clinical practice: a systematic mixed studies review protocol

open access: yesBJGP Open, 2021
Background: Generalist physician care is associated with improved patient outcomes. Despite initiatives to promote generalism in educational settings, recruitment to generalist disciplines remains less than required to serve societal needs.
Martina Kelly   +7 more
doaj   +1 more source

Clinical effectiveness and cost-effectiveness of cognitive behavioural therapy as an adjunct to pharmacotherapy for treatment-resistant depression in primary care: the CoBalT randomised controlled trial [PDF]

open access: yes, 2014
Background: Only one-third of patients with depression respond fully to treatment with antidepressant medication. However, there is little robust evidence to guide the management of those whose symptoms are 'treatment resistant'.<p></p> ...
Abel, Anna   +22 more
core   +4 more sources

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