Results 61 to 70 of about 4,004,716 (311)

Gatekeeping in Health Care [PDF]

We study the competitive effects of restricting direct access to secondary care by gatekeeping, focusing on the informational role of general practitioners (GPs).
Kurt R. Brekke, Odd Rune Straume, Robert Nuscheler   +2 more
core   +3 more sources

Identifying coping strategies used by patients at a transgender health clinic through analysis of free‐text autobiographical narratives

Health Expectations, 2021
Background This paper presents an analysis of 32 narratives written by patients waiting for assessment at a transgender health clinic (THC) in England. Narratives are autobiographical free texts, designed to allow patients to describe in their own words ...
Angela Zottola, Lucy Jones, Alison Pilnick, Louise Mullany, Walter Pierre Bouman, Jon Arcelus   +5 more
doaj   +1 more source

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

FEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo, Catherine S. Palmer, Jacqueline M. Kimmey   +2 more
wiley   +1 more source

Fatores associados à insatisfação dos usuários dos centros de especialidades odontológicas do Brasil em 2014: estudo transversal

Epidemiologia e Serviços de Saúde
Resumo Objetivo avaliar os fatores associados à insatisfação dos usuários dos centros de especialidades odontológicas (CEOs) do Brasil. Métodos estudo transversal, com dados do Programa de Melhoria do Acesso e da Qualidade dos CEOs; realizado em 2014,
Fabíola Bof de Andrade, Rafaela da Silveira Pinto   +1 more
doaj   +1 more source

An evaluation of the Wallasey Heart Centre [PDF]

, 2003
This project report discusses an evaluation of Wallasey Heart Centre, an intermediate cardiovascular clinic designed to provide accessible high-quality patient care to an area with a high prevalence of of coronary heart disease and poor access to ...
Jones, Jenny, Kirby, Karen, Perry, Catherine, Thurston, Miranda   +3 more
core  

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

FEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang, Satoshi Hashimoto, Sota Ito, Chisato Kikuguchi, Miho Hoshi, Kiyoshi Yamaguchi, Yoichi Furukawa, Toru Suzuki, Toshifumi Inada   +8 more
wiley   +1 more source

A review of certain recent advances in primary health care [PDF]

, 2014
A strong primary health care system is the keystone of health care and helps patients manage their health conditions in the community, whilst also providing disease prevention services.
Baldacchino, Marilyn, Bezzina, Glorianne, Sammut, Mario R., Scerri, Anne Marie   +3 more
core  

An occupational therapy intervention for residents with stroke related disabilities in UK care homes (OTCH): cluster randomised controlled trial [PDF]

, 2015
Objective To evaluate the clinical efficacy of an established programme of occupational therapy in maintaining functional activity and reducing further health risks from inactivity in care home residents living with stroke sequelae.
Barton, Garry, Burton, C. R., Burton, Christopher R., Fletcher-Smith, J., Fletcher-Smith, Joanna, Irvine, L., Irvine, Lisa, Lett, K., Mant, J., Mant, Jonathan, Masterson-Algar, Patricia, Peryer, G., Peryer, Guy, Rashid, Farzana, Roalfe, A. K., Roalfe, Andrea K., Sackley, Catherine M., Sharp, L., Sharp, Leslie, Sheehan, B., Sheehan, Bart, Stant, K. E., Stant, Katie E., Steel, Kerry, Steele, K., Walker, M. F., Walker, Marion F., Watkins, C. L., Watkins, Caroline L., Wheatley, K., Wheatley, Keith, Wilde, K., Wilde, Kate, Williams, Jane   +33 more
core   +5 more sources

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

FEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Strategies used for childhood chronic functional constipation: the SUCCESS evidence synthesis

Health Technology Assessment
Background Up to 30% of children have constipation at some stage in their life. Although often short-lived, in one-third of children it progresses to chronic functional constipation, potentially with overflow incontinence.
Alex Todhunter-Brown, Lorna Booth, Pauline Campbell, Brenda Cheer, Julie Cowie, Andrew Elders, Suzanne Hagen, Karen Jankulak, Helen Mason, Clare Millington, Margaret Ogden, Charlotte Paterson, Davina Richardson, Debs Smith, Jonathan Sutcliffe, Katie Thomson, Claire Torrens, Doreen McClurg   +17 more
doaj   +1 more source