Results 101 to 110 of about 3,439,590 (350)
A general model for analysis of linear and hyperbolic enzyme inhibition mechanisms
FEBS Open Bio, EarlyView.We developed a general enzyme kinetic model that integrates these six basic inhibition mechanism onto a single one. From this model, we deduced a general enzyme kinetic equation that through modulation of simple parameters, γ (the relative inhibitor affinity for two binding sites) and β (the reactivity of the enzyme–substrate–inhibitor complex), is ...
Rafael S. Chagas, Sandro R. Marana
wiley +1 more source
HSP70 governs permeability and mechanotransduction in primary human endothelial cells
FEBS Open Bio, EarlyView.HSP70 chemical inhibition reduces endothelial cell proliferation and increases permeability, the latter supported by normal interendothelial junctional protein distribution. HSP70 also plays a role in shear stress response, a hemodynamic force naturally present in blood vessels and correlated with vessel protection.
Andrea Pinto‐Martinez +5 more
wiley +1 more source
Does integrated science education improve scientific literacy?
JETEN, 2014 In Flanders, a choice has been made for the integrated school subject ‘Natural Sciences’, in ‘science for all’ secondary school trajectories, and for the three separate subjects biology, physics and chemistry, in trajectories for the future scientist and
Laura Tamassia, Renaat Frans
doaj
SHS Web of Conferences, 2016 The aim of this study was to determine the students’ mathematical and conceptual challenges for two important concepts of quantum mechanics and also to investigate how the students make sense of their solutions with the conceptual basis. In this context,
Özcan Özgür
doaj +1 more source
The evolution of the mood of the Izhevsk-Votkinsk workers in October 1917–December 1918 [PDF]
Омский научный вестник: Серия "Общество. История. Современность"The article examines the problem of determining the views of Izhevsk-Votkinsk workers in 1917–1918, which led them to participate in the anti-Soviet uprising of 1918.
N. A. Zayats
doaj +1 more source
Relevance of Life-Cycle Assessment in Context-Based Science Education: A Case Study in Lower Secondary School [PDF]
, 2019 Sakari Tolppanen +4 more
openalex +1 more source
Cloning, expression, purification, and structural modeling of the Chandipura virus matrix protein
FEBS Open Bio, EarlyView.This research protocol offers a guide for the cloning, expression, and purification of the Chandipura virus matrix protein using E. coli. It also includes a step‐by‐step procedure for cloning, expressing, and conducting fluorescence imaging of GFP‐fused Chandipura virus matrix protein in mammalian cell lines.
Mariana Grieben
wiley +1 more source
Homologous expression and purification of human HAX‐1 for structural studies
FEBS Open Bio, EarlyView.This research protocol provides detailed instructions for cloning, expressing, and purifying large quantities of the intrinsically disordered human HAX‐1 protein, N‐terminally fused to a cleavable superfolder GFP, from mammalian cells. HAX‐1 is predicted to undergo posttranslational modifications and to interact with membranes, various cellular ...
Mariana Grieben
wiley +1 more source
The Effect of Transitions on Access to Higher Education [PDF]
, 2009 Explores how the transition process from secondary to higher education affects access to higher education in the Netherlands, South Africa, Ukraine, and the United States. Examines barriers and makes recommendations for expanding "access with success.
Alexander Belyakov +3 more
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