Results 81 to 90 of about 10,944,705 (298)

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

open access: yesMolecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu   +13 more
wiley   +1 more source

Critical Issues in Reform and Inclusion of Youth with Disabilities in Secondary Education and Transition (NCSET Capacity Building Institute)

open access: yes, 2003
A transcript of a Capacity Building Institute (CBI) that provided researchers with an opportunity to engage in reflective dialogue around (1) Issues of reform, inclusion, and the intersection of reform and inclusion at the high school level; (2) Research
National Center on Secondary Education and Transition
core  

Sustaining pedagogical change via faculty learning community

open access: yesInternational Journal of STEM Education, 2019
Background The necessity of a science, technology, engineering, and math (STEM) literate population continues to be a high priority worldwide. One approach to build and bolster a STEM-literate workforce is to explore approaches for strengthening the ...
Teresa L. Tinnell   +3 more
doaj   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola   +11 more
wiley   +1 more source

Parenting Post-Secondary Students with Disabilities: Becoming the Mentor, Advocate, and Guide Your Young Adult Needs (NCSET Parent Brief)

open access: yes, 2002
A brief in English and Spanish focusing on the importance of involving parents in the transition from high school to the post-secondary environment, and providing concrete recommendations to help parents learn to mentor and advocate for their post ...
National Center on Secondary Education and Transition
core  

Being (Almost) a Mathematician: Teacher Identity Formation in Post-Secondary Mathematics [PDF]

open access: yes, 2009
Within the field of mathematics teacher education, mathematics graduate students have recently become subjects of investigation. While research in this area tends to focus on future schoolteachers, little has been done to examine prospective university ...
Beisiegel, Mary deRaeve
core   +1 more source

Secondary education.

open access: yes, 2000
The main focus of this report is on education expenditure and participation. The indicator most frequently referred to in public debates on expenditure is the percentage of GDP per country on education. A serious problem with this indicator is that it is affected by enrolment rates and the size of the youth population. A more sophisticated indicator is
openaire   +3 more sources

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

open access: yesMolecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim   +3 more
wiley   +1 more source

Special education needs and disabilities in secondary education (Switzerland)

open access: yes
https://www.becs-bloomsbury.com/article?docid=b-9781350934412&tocid=b-9781350934412-025&st=Special+Education+Needs+and+Disabilities+in+Secondary+Education+%28Switzerland ...
Mejeh, Mathias, Morinaj, Julia
core   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

open access: yesMolecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur   +11 more
wiley   +1 more source

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