Results 61 to 70 of about 1,256,135 (303)

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Transition, Secondary Education Reform, and Access to the General Education Curriculum (NCSET Capacity Building Institute)

, 2001
A transcript of a Capacity Building Institute (CBI) that was co-sponsored by NCSET and the Division on Career Development and Transition (DCDT) of the Council for Exceptional Children.
National Center on Secondary Education and Transition
core  

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

A survey on digital device engagement, digital stress, and coping strategies among college students in the Philippines

International Journal of Adolescence and Youth
This study surveyed 384 Filipino college students on their digital device engagement, digital stress, and coping strategies. Findings revealed that students were heavily reliant on digital devices.
Louie Giray, Jonard Nemeño, Jasmin Braganaza, Sheila May Lucero, Rex Bacarra   +4 more
doaj   +1 more source

The Ship in the Cave: The Greek and Nautical Origin of Buddhist Architecture

Journal of Asian Architecture and Building Engineering, 2020
Buddhist architecture rose during the time of the Greek influence in western India, but until today no relationship has been proved between both facts. If we accept that the Greeks stored their galleys overturning and placing them upon stanchions, as the
José M. Ciordia
doaj   +1 more source

Human capital theory and secondary education

, 1994
This paper critically examines the major assumptions underpinning current educational policies and argues that they are forging an unholy alliance between economic interests and education.
Down, B.
core  

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Current Challenges Facing the Future of Secondary Education and Transition Services for Youth with Disabilities in the United States (Discussion Paper)

, 2004
A paper promoting discussion among professionals, policymakers, employers, parents, and individuals with disabilities concerning current and future challenges facing secondary education and transition services nationally.This paper is based, in part, on ...
National Center on Secondary Education and Transition
core  

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

Molecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain, Yann Le Page, Frédéric Percevault, Emmanuelle Becker, Luc Negroni, Almudena Fernandez, Marta Cantero, Diego Muñoz‐Santos, Lluís Montoliu, Cyrille Garnier, Michael Primig   +10 more
wiley   +1 more source

Sustaining pedagogical change via faculty learning community

International Journal of STEM Education, 2019
Background The necessity of a science, technology, engineering, and math (STEM) literate population continues to be a high priority worldwide. One approach to build and bolster a STEM-literate workforce is to explore approaches for strengthening the ...
Teresa L. Tinnell, Patricia A. S. Ralston, Thomas R. Tretter, Mary E. Mills   +3 more
doaj   +1 more source