Results 61 to 70 of about 10,944,705 (298)

Comparative prevalence of different types of viral hepatitis in the district Dera Ismail Khan, Khyber Pakhtunkhwa, Pakistan

open access: yesEgyptian Liver Journal, 2022
Background Viral hepatitis causes both liver inflammation and damage and is a serious health problem. Methods The indoor data of different types of hepatitis were collected from the official records of the administration of District Head Quarter Hospital
Muhammad Ashraf Khan
doaj   +1 more source

A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma

open access: yesFEBS Letters, EarlyView.
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos   +9 more
wiley   +1 more source

Other title: Kansas Amended Accountability Workbook

open access: yes, 2008
Amended June 2008; Kansas' response for meeting the requirements of the No Child Left Behind Act has been incorporated within the workbook.; Submitted to U. S.
Kansas. State Department of Education.
core   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

open access: yesFEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward   +2 more
wiley   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

open access: yesMolecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce   +11 more
wiley   +1 more source

Effective pre-school, primary and secondary education project (EPPSE 3-14): influences on students' development in Key Stage 3: social-behavioural outcomes in Year 9 [PDF]

open access: yes, 2011
The Effective Pre-school, Primary and Secondary Education Project (EPPSE) has investigated the academic and social-behavioural development of approximately 3,000 children from the age of 3+ years since 1997.
Draghici, D.   +24 more
core   +1 more source

Assessment of the economics of production of weaner and grower rabbit fed sunflower seed meal (SFSM) based diets with or without Ronoxyme® HiPhos enzyme

open access: yesInternational Journal of Agricultural Research, Innovation and Technology
The cost-benefit analysis performance of weaner and grower rabbits fed processed sunflower (Helianthus annuus) seed meal (SFSM) and diets treated with enzymes in the research area was assessed.
Bosede Oluwatoyin Onazi   +2 more
doaj   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Transition, Secondary Education Reform, and Access to the General Education Curriculum (NCSET Capacity Building Institute)

open access: yes, 2001
A transcript of a Capacity Building Institute (CBI) that was co-sponsored by NCSET and the Division on Career Development and Transition (DCDT) of the Council for Exceptional Children.
National Center on Secondary Education and Transition
core  

Plato makes the team: the arrival of secondary school sport academies. [PDF]

open access: yes, 2002
Since sport captivates many young people in Aotearoa New Zealand, it is not surprising that it is being situated in a new form of educational setting. This is evidenced through the emergence of secondary school sport academies over the last four years ...
Pope, Clive C.
core  

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