Results 51 to 60 of about 1,256,135 (303)

Monthly and seasonal prevalence of asthma and chronic obstructive pulmonary disease in the District Dera Ismail Khan, Khyber Pakhtunkhwa, Pakistan

The Egyptian Journal of Bronchology, 2022
Background Asthma and chronic obstructive pulmonary disease are the major airway diseases and are increasingly important causes of mortality, morbidity, and disability globally.
Muhammad Ashraf Khan
doaj   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Teacher educational qualifications and the quality of teacher–student interactions in senior high school classrooms in Ghana: Could teacher self‐efficacy bridge the qualifications gap?

Future in Educational Research
Teacher qualifications, self‐efficacy, and quality of teacher–student interactions (QTSIs) are critical factors in educational discourse. While research shows varied results for each variable, studies have yet to examine all three variables ...
Albert Henry Ntarmah, Kwesi Yaro
doaj   +1 more source

Enhancing Formal Assessment Using Concept Cartoons in Physics: A Teacher’s Perspective

Science Education International
Fostering methods that promote learners’ conceptual understanding is crucial for better performance in science subjects. This study investigated how teachers of physical sciences perceive the utilization of Concept Cartoons as a formative evaluation tool.
William Zivanayi, Chinelo Georgina Candy Nwaigwe   +1 more
doaj   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source

A study of current practice in liaison between primary and secondary schools in physical education

, 2003
The purpose of this study was to investigate current practice in liaison between primary and secondary schools to promote continuity and progression in physical education during the transfer of pupils from Key Stage 2 to Key Stage 3 and to identify ...
Zwozdiak-Myers, P, Lawrence, J, Capel, S
core   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Assessment of the economics of production of weaner and grower rabbit fed sunflower seed meal (SFSM) based diets with or without Ronoxyme® HiPhos enzyme

International Journal of Agricultural Research, Innovation and Technology
The cost-benefit analysis performance of weaner and grower rabbits fed processed sunflower (Helianthus annuus) seed meal (SFSM) and diets treated with enzymes in the research area was assessed.
Bosede Oluwatoyin Onazi, Olajide Julius Filusi, Maikasuwa Zakariah   +2 more
doaj   +1 more source

Collective screening tools for early identification of dyslexia

Frontiers in Psychology, 2015
Current response to intervention models (RTI) favor a three-tier system. In general, Tier 1 consists of evidence-based, effective reading instruction in the classroom and universal screening of all students at the beginning of the grade level to identify
Olga Valéria Campana Dos Anjos Andrade, Paulo Estêvão Andrade, Simone Aparecida Capellini   +2 more
doaj   +1 more source