Results 121 to 130 of about 15,310,679 (339)

Analysis of Flow Meters Calibration [PDF]

, 2015
Calibration data of flow meters are often reported using the so called calibration coefficient, i.e. the ratio between the reference flow rate (or equivalent quantity, e.g.
SPAZZINI, PIER GIORGIO, PENNECCHI, FRANCESCA ROMANA, Pessana, Enrica, PICCATO, ALINE   +3 more
core  

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Time-resolved PIV investigation of the secondary instability of cross-flow vortices

, 2017
Time-resolved PIV measurements of the secondary instability modes of cross-flow vortices are presented. Measurements are performed on a large scale 45o swept wing at chord Reynolds number of 2.17 million in a low turbulence wind-tunnel facility.
Kotsonis M., Serpieri J.
core  

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

An Improved Physical Model for Open Channel Confluences: Bridging the Gap Between Laboratory and Field Observations

Water Resources Research
Despite decades of research on hydro‐morphodynamic processes at open‐channel confluences, significant discrepancies persist between flume experiments and field observations.
Keyu Li, Qingcheng Yu, Xudong Ma, Lu Wang, Ruihua Nie   +4 more
doaj   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

Molecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

CEACAM1 participation in breast cancer progression

Molecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin, Irina Kube‐Golovin, Anatolii Romaniuk, Gunther Wennemuth   +3 more
wiley   +1 more source

Homogenization of initial cell distribution by secondary flow of medium improves cell culture efficiency. [PDF]

PLoS One, 2020
Fukuma Y, Inui T, Imashiro C, Kurashina Y, Takemura K.   +4 more
europepmc   +1 more source

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

Molecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas, Barbara Karakyriakou, Patricia C. Muskus, Alyssa M. Roberts, Justin Rendleman, Alexa Warren, Hanxu Lu, Kimberly A. Birmingham, Malone K. Friedman, Abigail E. Goen, Huijuan Yang, Owen M. Wilkins, Fred W. Kolling, Eugene Demidenko, Julie M. Jorns, Brock C. Christensen, Todd W. Miller   +16 more
wiley   +1 more source

Turbulence Model Constant Calibration for Flow Field in Rod Bundle Based on Data Assimilation

Yuanzineng kexue jishu
The paper presents a novel approach to enhancing the accuracy of turbulence modeling in nuclear reactor simulations, specifically addressing secondary flow in the fuel assembly of pressurized water reactors.
LI Yi, QU Wenhai, XIONG Jinbiao
doaj   +1 more source