Meta‐analysis fails to show any correlation between protein abundance and ubiquitination changes
We analyzed over 50 published proteomics datasets to explore the relationship between protein levels and ubiquitination changes across multiple experimental conditions and biological systems. Although ubiquitination is often associated with protein degradation, our analysis shows that changes in ubiquitination do not globally correlate with changes in ...
Nerea Osinalde +3 more
wiley +1 more source
Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth +6 more
wiley +1 more source
Computational study of aortic hemodynamics for patients with an abnormal aortic valve: The importance of secondary flow at the ascending aorta inlet. [PDF]
Pirola S +7 more
europepmc +1 more source
Erythropoietin administration suppresses hepatic soluble epoxide hydrolase (sEH) expression, leading to increased CYP‐derived epoxides. This is associated with a shift in hepatic macrophage polarization characterized by reduced M1 markers and increased M2 markers, along with reduced hepatic inflammation, suppressed hepatic lipogenesis, and attenuated ...
Takeshi Goda +12 more
wiley +1 more source
The manifestation of vortical and secondary flow in the cerebral venous outflow tract: An in vivo MR velocimetry study. [PDF]
Kefayati S +8 more
europepmc +1 more source
Further experiments concerning secondary injection of gases into a supersonic flow [PDF]
Spaid, Frank W., Zukoski, Edward E.
core +1 more source
Secondary instabilities in compressible boundary layers [PDF]
Secondary instabilities are examined in compressible boundary layers at Mach numbers M(sub infinity) = 0, 0.8, 1.6, and 4.5. It is found that there is a broad-band of highly unstable 3-d secondary disturbances whose growth rates increase with increasing ...
Erlebacher, Gordon, Ng, Lian
core +1 more source
Matrix metalloproteinase‐9 (MMP9) drives ovarian cancer progression. Using MMP9‐null cells (M9‐KO) created from ovarian cancer cells, we found MMP9 loss did not block Epidermal Growth Factor (EGF)‐driven E‐cadherin dissolution or EMT but delayed and reduced EGF‐driven membrane protrusions. Transient MMP9 re‐expression drove membrane protrusion.
Claire Strauel +8 more
wiley +1 more source
Enhancing size based size separation through vertical focus microfluidics using secondary flow in a ridged microchannel. [PDF]
Tasadduq B +4 more
europepmc +1 more source
Nonsteady-Flow Thrust Augmenting Ejectors [PDF]
Ejector augmenters in which the transfer of mechanical energy from the primary to the secondary flow takes place through the work of interface pressure forces are investigated.
Foa, J. V.
core +1 more source

