Results 51 to 60 of about 815,665 (302)

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

ANALISIS SIFAT KIMIA GAMBUT PASCA KEBAKARAN DENGAN BERBAGAI UPAYA PEMULIHAN HUTAN DI KAWASAN HUTAN DENGAN TUJUAN KHUSUS (KHDTK) TUMBANG NUSA, KALIMANTAN TENGAH

JTSL (Jurnal Tanah dan Sumberdaya Lahan), 2020
Peat land has an important role, function, and benefit for human life, biodiversity, and global climate. The peat swamp forest in Central Kalimantan was devastated to a very large extent, which addresses the restoration of peat swamp forests, has ...
Fytria Kurniasari, Syahrul Kurniawan, Lenny Sri Nopriani, Dony Rachmanadi   +3 more
doaj   +1 more source

Identifying gene expression signatures for risk stratification of postoperative adjuvant chemotherapy in colorectal cancer

FEBS Open Bio, EarlyView.
A novel signature integrating genome‐wide analysis with clinical factors predicts recurrence in stage II colorectal cancer and enables a new risk stratification to guide postoperative adjuvant chemotherapy. Clinical risk stratification for postoperative recurrence in patients with pathological stage II (pStage II) colorectal cancer (CRC) is essential ...
Mayuko Otomo, Keisuke Okuno, Shuichi Watanabe, Sakiko Oba, Hiroyasu Kagawa, Masanori Tokunaga, Daisuke Ban, Yusuke Kinugasa   +7 more
wiley   +1 more source

Development of forest structure and leaf area in secondary forests regenerating on abandoned pastures in Central Amazonia [PDF]

, 2005
The area of secondary forest (SF) regenerating from pastures is increasing in the Amazon basin; however, the return of forest and canopy structure following abandonment is not well understood. This study examined the development of leaf area index (LAI),
Aide, Brown, Davidson, Elisa V. Wandelli, Eltahir, Erick C. M. Fernandes, Ewel, Fearnside, Fearnside, Feldpausch, Fernandes, Finegan, Gehring, Gerwing, Gerwing, Guariguata, Hartemink, Hegarty, Honzák, Hölscher, Jipp, Jordan, Kammesheidt, Kauffman, Kennard, Lucas, McWilliam, Meir, Mesquita, Moran, Nelson, Nepstad, Norman, Putz, Restom, Ribeiro, Saldarriaga, Schnitzer, Serrão, Steininger, Susan J. Riha, Ted R. Feldpausch, Uhl, Uhl, Uhl, Uhl, Veen, Vidal, Vieira, Vieira, Williams, Williamson, Wirth, Wright, Zarin, Zarin   +55 more
core   +1 more source

Old-growth forest loss and secondary forest recovery across Amazonian countries

Environmental Research Letters, 2021
There is growing recognition of the potential of large-scale restoration in the Amazon as a “nature-based solution” to climate change. However, our knowledge of forest loss and recovery beyond Brazil is limited, and carbon emissions and accumulation have not been estimated for the whole biome.
Charlotte C Smith, John R Healey, Erika Berenguer, Paul J Young, Ben Taylor, Fernando Elias, Fernando Espírito-Santo, Jos Barlow   +7 more
openaire   +3 more sources

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

FEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner, Hainan Zhu, Carol Christine Bosholm, Heuy‐Ching Wang, Tracy Criswell, Anthony Atala, Jian‐Xing Ma, Yuanyuan Zhang   +7 more
wiley   +1 more source

What is secondary forest?

Journal of Tropical Ecology, 1994
The recognition that tropical secondary forests are the tropical forests of the future has led to a rapid expansion in the literature. Unfortunately it has also resulted in an expansion in the meaning of the term 'secondary forest' which risks rendering it virtually useless.
openaire   +2 more sources

THE EXAMPLES OF FOREST MANAGEMENT IN SECONDARY FORESTS OF WESTERN SIBERIA

Сибирский лесной журнал, 2017
Identifying the best practices of responsible and sustainable forest use is an important aspect for possible learning of experience and replication of the most interesting examples in forestry. Qualitative and timely reforestation of disturbed areas with economically valuable species is the key indicator for the performance of effective forest ...
N. M. Debkov, A. V. Bryukhanov
openaire   +2 more sources

Shared Genetic Effects and Antagonistic Pleiotropy Between Multiple Sclerosis and Common Cancers

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Epidemiologic studies have reported inconsistent altered cancer risk in individuals with multiple sclerosis (MS). Factors such as immune dysregulation, comorbidities, and disease‐modifying therapies may contribute to this variability.
Asli Buyukkurt, Marius Ygonia, Ali Manouchehrinia, Philippe Lefrançois, Ingrid Kockum, Adil Harroud   +5 more
wiley   +1 more source

Forest ecosystem-service transitions: the ecological dimensions of the forest transition

Ecology and Society, 2017
New forests are expanding around the world. In many regions, regrowth rates are surpassing deforestation rates, resulting in "forest transitions," or net gains in forest cover.
Sarah Jane. Wilson, John Schelhas, Ricardo Grau, A. Sofía. Nanni, Sean Sloan   +4 more
doaj   +1 more source