Results 81 to 90 of about 6,211,757 (240)

DESAIN PERANGKAT-KERAS KOMPONEN PENDUKUNG PENGEMBANGAN RADAR SEKUNDER UNTUK TRACKING TIGA DIMENSI TRAYEKTORI UJI COBA ROKET

open access: yesTeknik, 2012
Topic executed by is " Development of Secondary Radar For The Tracking Of Three Dimension Trajectory Test-Drive The National Rocket".In first year of research focussed at desain and making of component of hardware of producer of radio frequency 900 MHZ ...
Darjat Darjat
doaj  

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

open access: yesMolecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu   +13 more
wiley   +1 more source

Wideband Burst-by-Burst Adaptive Modulation Using Reduced-Complexity In-Phase/Quadrature-Phase Turbo Equalization

open access: yes, 2002
The performance of burst-by-burst adaptive modulation is studied in conjunction with reduced complexity turbo equalization over a wideband multi-path Rayleigh fading channel.
Wong, C H, Yeap, B L, Hanzo, L
core   +1 more source

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

open access: yesMolecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington   +10 more
wiley   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

open access: yesMolecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq   +8 more
wiley   +1 more source

Effects of low-frequency burst stimulation of the motor thalamus on cortical neural co-firing

open access: yesBrain Stimulation
Background: Electrical stimulation targeting the motor thalamus (Mthal) represents an emerging strategy for regulating motor cortical activity patterns, however the fundamental mechanisms and optimal stimulation configurations are not well established ...
Kyungsoo Kim   +5 more
doaj   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

open access: yesMolecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang   +9 more
wiley   +1 more source

Improving Broadcast Channel Rate Using Hierarchical Modulation [PDF]

open access: yes, 2012
We investigate the design of a broadcast system where the aim is to maximise the throughput. This task is usually challenging due to the channel variability.
Méric, Hugo   +4 more
core  

Rake Receiver Detection of Adaptive Modulation Aided CDMA over Frequency Selective Channels

open access: yes, 2001
A closed form Bit Error Ratio (BER) formula is derived for a fixed-mode Quadrature Amplitude Modulation (QAM) scheme employing Rake receivers and receiver antenna diversity.
Choi, B.J., Hanzo, L.
core   +1 more source

CEACAM1 participation in breast cancer progression

open access: yesMolecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin   +3 more
wiley   +1 more source

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