Results 81 to 90 of about 3,993,593 (292)

The EXPLAIN Study: Exploring Arthrogryposis Multiplex Congenita in Adults in Norway — A Description of Demographic, Medical, and Neurological Findings

American Journal of Medical Genetics Part C: Seminars in Medical Genetics, EarlyView.
ABSTRACT Arthrogryposis Multiplex Congenita (AMC) encompasses several hundred conditions with diverse genetic, pathophysiological, and clinical origins. The overarching EXPLAIN study explores underlying causes and implications of AMC and represents the largest clinical cohort of adults with AMC reported to date.
My Vuong Hermansen, Kristin Ørstavik, Unni Steen, Mathias Toft, Cathrine Brunborg, Lena Lande Wekre   +5 more
wiley   +1 more source

Evaluation of a guideline-anchored retrieval-augmented generation (RAG) system for headache diagnosis and management: A case-vignette study

Medicine Science
Headache disorders are frequently misdiagnosed, because of diagnostic criteria complexity. This study aimed to evaluate the diagnostic accuracy, safety, and usability of a guideline-anchored retrieval-augmented generation (RAG) clinical decision support ...
Gulcin Babaoglu
doaj   +1 more source

Caregiver Reports on the Needs and Experiences of Children Impacted by Parental Incarceration: Results From an Australian Survey

Australian Journal of Social Issues, EarlyView.
ABSTRACT Children experiencing parental imprisonment are known to be among the most overlooked in our community. They often experience multiple and compounding disadvantages, with long‐term consequences, but receive no specialised assistance. Knowledge about these children and their families is lacking in Australia and is required to inform policy ...
Catherine Flynn, Lana Battaglia, Lorana Bartels, Susan Dennison, Susy Harrigan, Lee Huggins, Sofia Grage‐Moore   +6 more
wiley   +1 more source

Elevated blood pressure and headache disorders in China - associations, under-treatment and implications for public health. [PDF]

, 2015
BACKGROUND: Both hypertension (HTN) and headache disorders are highly prevalent worldwide. Our purpose, in a nationwide study of the Chinese general population, was to evaluate any association between primary headache disorders and elevated blood ...
Zhao, G, Fang, Y, Steiner, TJ, Yang, Xiaosu, Fang, Yannan, Liu, R, Yang, X, Cao, X, Qiao, X, Yu, Shengyuan, Steiner, Timothy J., Qiao, Xiangyang, Feng, J, Liu, Ruozhuo, Feng, Jiachun, He, M, He, MianWang, Cao, Xiutang, Zhao, Gang, Yu, S   +19 more
core   +1 more source

Cohesion Without Consensus: Attitudinal Profiles of Social Cohesion in Australia

Australian Journal of Social Issues, EarlyView.
ABSTRACT Headline indicators of social cohesion in Australia have remained stable in recent years despite rising political polarisation and declining institutional trust worldwide. Yet recent protests and incidents of ethnically and politically motivated violence suggest that cohesion may be under strain. If cohesion is understood not as the pursuit of
John van Kooy
wiley   +1 more source

T Cell‐Mediated Targeting of Interneurons in Mice Shapes Hippocampal Remodeling and Epilepsy

Annals of Neurology, EarlyView.
Objective Autoimmune encephalitis (AE) is associated with autoantibodies targeting distinct neuronal populations. In AE, antibodies against glutamate decarboxylase 65 (GAD65), expressed in GABAergic interneurons, are frequently detected. In GAD65‐AE, hippocampal biopsies often show infiltrates of CD8+ cytotoxic T cells (CTLs), suggesting a prominent T ...
Daniel S. Galvis‐Montes, Lukas Henning, Karen M. J. van Loo, Rainer Surges, Susanne Schoch, Albert J. Becker, Julika Pitsch   +6 more
wiley   +1 more source

Patient‐Derived Fibroblasts as a Clinically Relevant Model of Kearns–Sayre Syndrome

Annals of Neurology, EarlyView.
Objective Kearns–Sayre syndrome (KSS) is characterized by single large‐scale mitochondrial DNA deletions and by severe early‐onset clinical manifestations with neurological involvement. Reliable disease models, as well as validated biomarkers or effective treatments, are lacking.
Laura Valls‐Roca, Adrià Vilaseca‐Capel, Judith Cantó‐Santos, Ester Tobías, Félix Andújar‐Sánchez, Laia Farré‐Tarrats, Frederic Tort, Carles Rentero, Carlos Enrich, Virginia López, Juan R. Tejedor, Anna Esteve‐Codina, Cristina Núñez de Arenas, Pedro J. Moreno‐Lozano, José C. Milisenda, Mar O'Callaghan, Teresa García‐Silva, Montserrat Morales‐Conejo, Mario F. Fraga, Rafael Artuch, Miguel Á. Martín, José M. Cuezva, Ana Matas, Glòria Garrabou, Mariona Guitart‐Mampel   +24 more
wiley   +1 more source

The association between headache and low back pain: a systematic review

The Journal of Headache and Pain, 2019
Background To systematically review studies quantifying the association between primary chronic headaches and persistent low back pain (LBP). Main text We searched five electronic databases.
Arani Vivekanantham, Claire Edwin, Tamar Pincus, Manjit Matharu, Helen Parsons, Martin Underwood   +5 more
doaj   +1 more source

Growth Differentiation Factor 15 as a Cerebrospinal Fluid Biomarker for the Diagnosis and Prognosis of Leptomeningeal Metastasis

Annals of Neurology, EarlyView.
Objective As leptomeningeal metastasis (LM) has a poor prognosis, reliable cerebrospinal fluid (CSF) diagnostic biomarkers are urgently needed. This study evaluated the diagnostic value of CSF growth differentiation factor 15 (GDF15) in LM from lung adenocarcinoma (LUAD) and breast cancer (BC).
Haoyu Ruan, Jie Li, Fuhai Wang, Lei Zhang, Jie Luo, Yuan Mu, Ting Wang, Yuqing Wu, Jingping Liu, Yunyun Ning, Xuan Deng, Ming Guan, Jian Xu   +12 more
wiley   +1 more source

Gastrointestinal Headache; a Narrative Review

Emergency, 2016
There are studies reporting primary headaches to be associated with gastrointestinal disorders, and some report resolution of headache following the treatment of the associated gastrointestinal disorder.
Majid T Noghani, Hossein Rezaeizadeh, Sayed Mohammad Baqer Fazljoo, Mahmoud Yousefifard, Mansoor Keshavarz   +4 more
doaj