Results 111 to 120 of about 2,838,050 (235)
Genetic Resilience and Resistance in Alzheimer's Disease Diagnosis and Pathology
Annals of Neurology, EarlyView.Objective Some individuals avoid Alzheimer's disease (AD) pathology as they age, or retain cognition despite substantial pathology, suggesting mechanisms of resistance or resilience to neurodegeneration. Educational attainment (EA) is associated with reduced risk of cognitive decline, although the underlying mechanisms remain unclear.
Ganna Leonenko +8 more
wiley +1 more source
Annals of Neurology, EarlyView.Objective The objective of this study was to explore the association between 18 kDa translocator protein (TSPO)‐positron emission tomography (PET)–measurable glial activation and serum chitotriosidase (CHIT1) in people with multiple sclerosis (pwMS), and its expression in postmortem MS brain tissue.
Venla Ahola +14 more
wiley +1 more source
Common primary headaches in pregnancy
, 2015 Headache is a very common problem in pregnancy. Evaluation of a complaint of headache requires categorizing it as primary or secondary. Migrainous headaches are known to be influenced by fluctuation of estrogen levels with high levels improving it and ...
Amitava Rudra, Anuradha Mitra
core +1 more source
Annals of Neurology, EarlyView.Background The operational definition and imaging assessment of the no‐reflow phenomenon, a potential contributor to poor clinical outcome despite successful thrombectomy, remains debated. We aimed to develop expert‐based international consensus on the definition, assessment, and reporting standard of cerebral no‐reflow post‐thrombectomy. Methods Three‐
Adnan Mujanovic +21 more
wiley +1 more source
A Possible Newly Defined and Treatable Secondary Cause of Early Morning Wake-Up Headaches in an Older Hypermobile Woman: Nutcracker Physiology with Spinal Epidural Venous Congestion [PDF]
Introduction Left renal vein compression (nutcracker physiology) with secondary spinal epidural venous congestion is a newly recognized cause of daily persistent headache.
DeLisa Fairweather +4 more
core +1 more source
Editorial: Functional and Structural Brain Alterations in Headache: A Trait or a State?
Frontiers in Neurology, 2020 Roberta Messina +6 more
doaj +1 more source
Annals of Neurology, EarlyView.Objective Identification of cerebral amyloid angiopathy (CAA) before its hemorrhagic manifestations remains limited. We aimed to determine whether severe enlarged perivascular spaces in the centrum semiovale (EPVS‐CSO) identify a prehemorrhagic stage of sporadic CAA by predicting the first appearance of CAA‐related hemorrhagic lesions or incident ...
Baris Alten +8 more
wiley +1 more source
Astrocyte SMN Restoration and Forskolin Treatment Improve SMA Synaptic Pathology
Annals of Neurology, EarlyView.Objective Early phenotypic presentation of central afferent synapse dysfunction within patients with spinal muscular atrophy (SMA) represents a key target for therapeutic development; however, the underlying disease mechanisms remain unresolved. By further investigating motor neuron synapse and peri‐synaptic astrocyte process (PAP) defects in human SMA
Emily Welby +6 more
wiley +1 more source
A retrospective analysis of the headache associated with temporomandibular joint disorder [PDF]
, 2012 Headache is a common symptom, that can be extremely disabling, affecting 26 million of patients only in Italy. ICHD-II has reported two categories: "primary headaches" and "secondary headaches".
Riccardi, E. +19 more
core
Annals of Neurology, EarlyView.Objective Epigenetic clocks are biomarkers of biological aging influenced by lifestyle and systemic factors. Accelerated epigenetic aging has been associated with neurodegeneration, but its relevance in frontotemporal dementia is unclear. We investigated biological aging in frontotemporal dementia using the GrimAge2 epigenetic clock, a DNA methylation ...
Daphne Nijland +9 more
wiley +1 more source