Results 91 to 100 of about 3,127,419 (312)

The Scottish school leavers cohort: linkage of education data to routinely collected records for mortality, hospital discharge and offspring birth characteristics [PDF]

, 2017
Purpose: The Scottish school leavers cohort provides population-wide prospective follow-up of local authority secondary school leavers in Scotland through linkage of comprehensive education data with hospital and mortality records.
Dundas, Ruth, Leyland, Alastair H., Stewart, Catherine H.   +2 more
core   +1 more source

Th e concept of quality in the function of secondary health care

Ekonomski Vjesnik, 2017
The paper brings an overview of basic approaches to the concept of quality and quality management in order to improve secondary health care. We observe the concept of quality from the perspective of accreditation, categorization and certification of health institutions in the secondary health care.
Aleksijević, Agneza, Šebo, Damir, Aleksijević, Marko   +2 more
openaire   +3 more sources

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

Molecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns, Jaclyn S. Long, Sergio Lilla, Kelly Hodge, Marcus J. G. W. Ladds, Colin Nixon, Paula Fernández‐Palanca, Sara Zanivan, Pilar Acedo, Stephen P. Pereira, Kevin M. Ryan   +10 more
wiley   +1 more source

Demand for health care in HIV/AIDS – affected households in two communities in the Free State province of South Africa [PDF]

This paper analyses differences in the choice of health care facility by ill individuals in HIV/AIDS-affected households in the Free State province of South Africa.
Frikkie Booysens, Martine Visser
core   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source

A governance model for integrated primary/ secondary care for the health-reforming first world: results of a systematic review [PDF]

, 2013
Internationally, key health care reform elements rely on improved integration of care between the primary and secondary sectors. The objective of this systematic review is to synthesise the existing published literature on elements of current integrated ...
A Harden, B Hutchison, C Ham, C Nicholson, Caroline Nicholson, CL Jackson, CL Jackson, CL Jackson, CL Jackson, CL Jackson, Claire Jackson, Commonwealth of Australia, Commonwealth of Australia, Commonwealth of Australia, DR Rittenhouse, E Nolte, E Suter, G Powell Davies, GA Armitage, GR Baker, I Featherstone, J Cumming, J Noyes, J Ovretveit, John Marley, L Smyth, LL Pederson, M Connor, M Dixon-Woods, M Harris, M Sandelowski, Ministry of Health, R Rosen, R Wedel, RA Paulus, RAND Europe, Ernst & Young LLP, RJ Fraschetti, S Peskett, S Shaw, Scottish Executive, The NHS Confederation   +40 more
core   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Initial Experiences of Building Secure Access to Patient Confidential Data via the Internet [PDF]

, 2000
A project to enable health care professionals (GPs, practice nurses and diabetes nurse specialists) to access, via the Internet, confidential patient data held on a secondary care (hospital) diabetes information system, has been implemented.
Chadwick, David W., Harvey, S., New, John, Young, Andrew J.   +3 more
core  

Effectiveness of Community Based Safe Motherhood Promoters in Improving the Utilization of Obstetric care. The Case of Mtwara Rural District in Tanzania. [PDF]

, 2010
In Tanzania, maternal mortality ratio remains unacceptably high at 578/100,000 live births. Despite a high coverage of antenatal care (96%), only 44% of deliveries take place within the formal health services.
Declare Mushi, Rose Mpembeni, Albrecht Jahn, UNICEF, ICM/FIGO, UN, National Bureau of Statistics, SN Massawe, F Font, National Bureau of Statistics {Tanzania} & Macro International Inc. 1997, E Urassa, KM Moore, S Thaddeus, RS Ross, M Kowalewski, M Rosato, J Elder, A Kleinman, MotherCare Matters, E Murray, C Santarelli, WHO, SB Rifkin, T Lankester, B Nwakoby, JS Kiwanuka, United Nation., A Jahn, D Mushi, J Lennon, D Werner, Tanzania Ministry of Health, District Medical Officer, E Essien, U Lehmann, HB Kendah, BN Nwakoby, S Jessop, S Rowland, B Kunene, BC Mullany, District Medical Officer, G Walraven, M Thorogood   +43 more
core   +3 more sources

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source