Results 91 to 100 of about 47,738 (289)

Lysophosphatidic Acid Synergizes With 1,25‐Dihydroxyvitamin D to Promote Fibroblast Growth Factor‐23 Synthesis via MAPK Signaling and Induction of the IL12A Gene

open access: yesThe FASEB Journal, Volume 40, Issue 1, 15 January 2026.
Ay et al. investigated the cellular mechanisms behind the role of lysophosphatidic acid (LPA) in FGF23 production. They revealed that LPA cooperates with 1,25‐dihydroxyvitamin D (1,25D), that is, the bioactive form of vitamin D known to stimulate FGF23 synthesis. This synergy entails MAPK signaling and the induction of the gene encoding the interleukin‐
Birol Ay   +7 more
wiley   +1 more source

Bradycardia secondary to primary hyperparathyroidism

open access: yesJournal of International Medical Research, 2019
Clinical doctors rarely associate hyperparathyroidism with significant bradyarrhythmia. We report a rare case of a patient initially misdiagnosed with primary sick sinus syndrome, which was eventually shown to be secondary to primary hyperparathyroidism.
Fei Liu   +3 more
doaj   +1 more source

Calciphylaxis following kidney transplantation: a case report [PDF]

open access: yes, 2009
Introduction: Calciphylaxis occurring after kidney transplantation is rare and rarely reported. It results in chronic non-healing wounds and is associated with a poor prognosis and is often fatal.
Andrew R Ready   +15 more
core   +4 more sources

Treatment with Minicircle DNA Expressing a FGF23 Fragment in a Clinically relevant Mouse Model of X‐Linked Hypophosphatemic Rickets

open access: yesAdvanced Science, Volume 13, Issue 4, 19 January 2026.
The pathogenic role of PHEX isn't fully determined, and there is no radical cure for X‐linked hypophosphatemic rickets (XLHR). This study makes the first attempt to perform gene therapy using a minicircle DNA (MC‐DNA) vector expressing a fragment of FGF23 (amino acids 180‐251) in Phex‐T1349C mice and suggests MC‐DNA as a promisingly safe and effective ...
Huixiao Wu   +20 more
wiley   +1 more source

A Swelling in the Mouth in a Chronic Hemodialysis Patient

open access: yesCase Reports in Nephrology, 2016
Oral manifestations of severe secondary hyperparathyroidism include maxillary and mandibular deformities, brown tumors, dental abnormalities, and metastatic calcification of soft tissues.
Arnaud Devresse   +3 more
doaj   +1 more source

A Giant Parathyroid Adenoma Presenting as Coughs and Dyspnea in a Young Woman: A Case Report

open access: yesClinical Case Reports, Volume 14, Issue 1, January 2026.
ABSTRACT A parathyroid adenoma is defined as a benign tumor in the parathyroid glands. A type of parathyroid adenoma is giant parathyroid adenoma that weighs > 3.5 g and has a size of more than 2 cm. A 37‐year‐old woman presented with coughs and dyspnea without fever, hemoptysis, and weight loss. Examination of the patient revealed a diffusely enlarged
Somayeh Chahkandi   +3 more
wiley   +1 more source

Secondary Hyperparathyroidism [PDF]

open access: yesAnnals of Clinical Biochemistry: International Journal of Laboratory Medicine, 1993
M J, McKenna, R, Freaney
openaire   +2 more sources

Burosumab in Unidentifiable Tumor‐Induced Osteomalacia

open access: yesClinical Case Reports, Volume 14, Issue 1, January 2026.
ABSTRACT Tumor‐induced osteomalacia (TIO) can be challenging due to underlying tumors being either unresectable or unidentifiable. Burosumab, an anti‐FGF23 monoclonal antibody, has been proven to be effective in treating TIO but is currently not subsidized for this indication in Australia.
Yi Shan Der   +5 more
wiley   +1 more source

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