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American Journal of Kidney Diseases, 2020
RATIONALE & OBJECTIVE Although multiple lines of evidence suggest a negative impact of secondary hyperparathyroidism on patients with kidney failure treated by hemodialysis, it is uncertain whether patients can detect associated symptoms.
A. Levy +8 more
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RATIONALE & OBJECTIVE Although multiple lines of evidence suggest a negative impact of secondary hyperparathyroidism on patients with kidney failure treated by hemodialysis, it is uncertain whether patients can detect associated symptoms.
A. Levy +8 more
semanticscholar +1 more source
Mechanisms of secondary hyperparathyroidism
American Journal of Physiology-Renal Physiology, 2002Small decreases in serum Ca2+and more prolonged increases in serum phosphate (Pi) stimulate the parathyroid (PT) to secrete parathyroid hormone (PTH), and 1,25(OH)2D3decreases PTH synthesis and secretion. A prolonged decrease in serum Ca2+and 1,25(OH)2D3, or increase in serum Pi, such as in patients with chronic renal failure, leads to the appropriate ...
Tally Naveh-Many +2 more
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Hyperparathyroidism Secondary to Hyperaldosteronism
High Blood Pressure & Cardiovascular Prevention, 2010Introduction: Hyperparathyroidism has been associated with essential hypertension. In rats, volume expansion, the deoxycorticosterone (DOC)-salt hypertension model and primary aldosteronism cause a reduction in plasma calcium levels and secondary hyperparathyroidism. In these rats, urinary calcium decreases with thiazides and/or aldosterone antagonists,
Fortina F., Bellosta S.
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Secondary and Tertiary Hyperparathyroidism
Journal of Clinical Densitometry, 2013We reviewed the etiology and management of secondary and tertiary hyperparathyroidism. Secondary hyperparathyroidism is characterized by an increase in parathyroid hormone (PTH) that is appropriate and in response to a stimulus, most commonly low serum calcium. In secondary hyperparathyroidism, the serum calcium is normal and the PTH level is elevated.
Sophie A. Jamal, Paul D. Miller
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Secondary Hyperparathyroidism: Pathogenesis and Latest Treatment
Therapeutic apheresis and dialysis, 2018The classic pathogenesis of secondary hyperparathyroidism (SHPT) began with the trade‐off hypothesis based on parathyroid hormone hypersecretion brought about by renal failure resulting from a physiological response to correct metabolic disorder of ...
Masahide Mizobuchi, H. Ogata, F. Koiwa
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Anemia and Secondary Hyperparathyroidism
Archives of Internal Medicine, 1978Anemia has been recognized recently as a possible complication of primary hyperparathyroidism. If the hyperparathyroid state can induce anemia in patients with normal kidney function, the extremely high levels of circulating parathyroid hormone usually observed in hyperparathyroidism secondary to chronic renal failure may have an unfavorable influence ...
Paul Jungers +5 more
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Management of Secondary Hyperparathyroidism
Therapeutic Apheresis and Dialysis, 2005Abstract: Secondary hyperparathyroidism (SHPT) remains an inevitable consequence of untreated chronic uremia. It is the result of a combination of phosphate (P) retention, failure of calcitriol synthesis, and hypocalcemia. Therapies used to correct these abnormalities, namely active vitamin D replacement, calcium (Ca) supplementation, and phosphate (P)
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Cimetidine in Secondary Hyperparathyroidism
Annals of Internal Medicine, 1982Excerpt To the editor: After anecdotal reports on a decrease of immunoreactive paraphyroid hormone (PTH) levels due to the administration of cimetidine in primary hyperparathyroidism (1,2), therape...
J. Kovarik +3 more
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The prevention of secondary hyperparathyroidism
Current Opinion in Nephrology and Hypertension, 1993It has become increasingly evident that clear-cut disturbances of bone and mineral metabolism develop early in renal failure. Among these disturbances, hyperparathyroidism is well documented and is usually asymptomatic at that early stage. It is now accepted that early therapy using phosphate restriction, through diet and calcium-containing phosphate ...
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Secondary hypercalcemic hyperparathyroidism
Virchows Archiv Abteilung A Pathologische Anatomie, 1973A search was made for patients with associated secondary hyperparathyroidism and hypercalcemia: 22 such cases were found in the literature and 22 were recorded among 92 patients operated upon because of parathyroid disease. In the remaining 70 patients the effect of the operation on the serum calcium level was investigated: persisting hypercalcemia ...
Leif Bergdahl, Lennart Boquist
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