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Engineering of Secondary Metabolism
Annual Review of Genetics, 2015Secondary (specialized) metabolites, produced by bacteria, fungi, plants, and other organisms, exhibit enormous structural variation, and consequently display a wide range of biological activities. Secondary metabolism improves and modulates the phenotype of the host producer.
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Secondary metabolism in cannabis
Phytochemistry Reviews, 2008Cannabis sativa L. is an annual dioecious plant from Central Asia. Cannabinoids, flavonoids, stilbenoids, terpenoids, alkaloids and lignans are some of the secondary metabolites present in C. sativa. Earlier reviews were focused on isolation and identification of more than 480 chemical compounds; this review deals with the biosynthesis of the secondary
Isvett Josefina Flores-Sanchez +1 more
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1999
Biotechnological exploitation of plant cell cultures for production of natural products will depend on our ability to modify expression of complex biosynthetic pathways both quantitatively and qualitatively. De novo, transcriptional activation of genes encoding biosynthetic pathway enzymes represents the first, and often the major, control point for ...
Paul J. Howles +6 more
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Biotechnological exploitation of plant cell cultures for production of natural products will depend on our ability to modify expression of complex biosynthetic pathways both quantitatively and qualitatively. De novo, transcriptional activation of genes encoding biosynthetic pathway enzymes represents the first, and often the major, control point for ...
Paul J. Howles +6 more
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Secondary metabolism in the lichen symbiosis
Chemical Society Reviews, 2018Lichens, which are defined by a symbiosis between a mycobiont (fungal partner) and a photobiont (photoautotrophic partner), are in fact complex assemblages of microorganisms that constitute a largely untapped source of bioactive secondary metabolites.
Mark J. Calcott +5 more
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Origins of secondary metabolism.
Ciba Foundation symposium, 1993Secondary metabolites generally benefit their producers as poisons that protect them against competitors, predators or parasites. They are produced from universally present precursors (most often acetyl-CoA, amino acids or shikimate) by specific enzymes that probably arose by the duplication and divergence of genes originally coding for primary ...
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Secondary metabolism in simulated microgravity
The Chemical Record, 2001AbstractWe have studied microbial secondary metabolism in a simulated microgravity (SMG) environment provided by NASA rotatingâwall bioreactors (RWBs). These reactors were designed to simulate some aspects of actual microgravity that occur in space. Growth and product formation were observed in SMG in all cases studied, i.e., Bacillus brevis produced ...
Aiqi Fang, Arnold L. Demain
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1984
In addition to the primary metabolic reactions which are similar in all groups of living organisms (formation and breakdown of nucleic acids and proteins and their precursors, of most carbohydrates, of some carboxylic acids, etc., cf. Table 6), a vast number of metabolic pathways lead to the formation of peculiar chemical compounds, the so-called ...
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In addition to the primary metabolic reactions which are similar in all groups of living organisms (formation and breakdown of nucleic acids and proteins and their precursors, of most carbohydrates, of some carboxylic acids, etc., cf. Table 6), a vast number of metabolic pathways lead to the formation of peculiar chemical compounds, the so-called ...
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SECONDARY METABOLISM AS DIFFERENTIATION
Journal of Food Safety, 1983Secondary metabolism is the biosynthesis, transformation, and degradation of a wide array of natural products. These low molecular weight organic compounds are generally produced at a restricted phase of the life cycle, often in association with differentiated morphological structures.
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Adventitious Roots and Secondary Metabolism
Chinese Journal of Biotechnology, 2008Plants are a rich source of valuable secondary metabolites and in the recent years plant cell, tissue and organ cultures have been developed as an important alternative sources for the production of these compounds. Adventitious roots have been successfully induced in many plant species and cultured for the production of high value secondary ...
Kee-Yoeup Paek +2 more
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Transcriptional regulation of secondary metabolism
Functional Plant Biology, 2003Plants produce secondary metabolites during development and in response to environmental stimuli such as light or pathogen attack. Transcriptional regulation provides the most important control point for the secondary metabolic pathways studied to date. In this article we review the data on the transcription factors that modulate this regulation.
Kevin M. Davies, Kathy E. Schwinn
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