Results 121 to 130 of about 3,541,226 (351)

An Innovative “Tooth‐On‐Chip” Microfluidic Device Emulating the Structure and Physiology of the Dental Pulp Tissue

Advanced Healthcare Materials, EarlyView.
This work presents a “tooth‐on‐chip” device that mimics dental pulp tissue. By co‐culturing key cell types, it recreates vascular networks, stem cell niches, the odontoblast/dentine interface, and trigeminal innervation. This innovative platform provides a unique model of dental pulp structure and physiology, with significant potential for accelerating
Alessandro Cordiale, Deborah Stanco, Roberta Visone, Bernd Stadlinger, Pierfrancesco Pagella, Marco Rasponi, Thimios A. Mitsiadis   +6 more
wiley   +1 more source

Aspergillus Secondary Metabolite Database, a resource to understand the Secondary metabolome of Aspergillus genus

Scientific Reports, 2017
Aspergillus is a genus of ubiquitous fungi that are pathologically & therapeutically important. Aspergillus Secondary Metabolites Database (A2MDB) is a curated compendium of information on Aspergillus & its secondary metabolome. A2MDB catalogs 807 unique
V. Vadlapudi, Nabajyoti Borah, Kanaka Raju Yellusani, Sriramya Gade, Prabhakar Reddy, Maheshwari Rajamanikyam, Lakshmi Narasimha Santosh Vempati, Satya Prakash Gubbala, P. Chopra, Suryanarayana Murty Upadhyayula, Ramars Amanchy   +10 more
semanticscholar   +1 more source

A Novel Microfluidic System for 3D Epidermis and Full‐Thickness Skin Growth for Nanoparticle Safety Assessment

Advanced Healthcare Materials, EarlyView.
This work presents a novel, dynamically perfused, configurable microfluidic system for epidermis‐only (E and full‐thickness skin (FT SoC) growth, emulating human skin structure and barrier function. Upon TiO2 nanoparticle exposure, the system reveals compromised barrier integrity, reduced metabolic activity, increased permeability, and chemokine‐driven
Samantha Costa, Ana B. Carneiro, Filipa Lebre, João Meneses, Alar Ainla, Cacilda Moura, Ernesto Alfaro‐Moreno, Ana R. Ribeiro   +7 more
wiley   +1 more source

PECULIARITIES OF SECONDARY METABOLITES BIOSYNTHESIS IN PLANT CELL CULTURES

International Journal of Secondary Metabolite, 2016
Plant cell culture is traditionally viewed as a unique artificially created biological system represented a heterogenous population of dedifferentiated cells.
A.M. NOSOV
doaj  

The Effect of Seawater Used for Hydrodistillation on Essential Oil Yield and Composition of Oil-Bearing Rose (Rosa damascena Mill.)

International Journal of Secondary Metabolite, 2017
Oil-bearing rose (Rosa damascena Mill.) is the most important rose species having a high-value volatile oil, used in the fragrance and cosmetic industries. Epidermal cells of the flower petals are the main essential oil source. During the boiling process
Nimet Kara, Sabri Erbaş, Hasan Baydar   +2 more
doaj   +1 more source

Ascorbic Acid Modulates Collagen Properties in Glucocorticoid‐Induced Osteoporotic Bone: Insights into Chemical, Mechanical, and Biological Regulation

Advanced Healthcare Materials, EarlyView.
Osteoporosis from long‐term glucocorticoid (GIOP) use elevates susceptibility to fracture. This study shows GCs impair ascorbic acid (AA) metabolism in osteoblasts, collagen synthesis and extracellular matrix integrity. AA enhanced collagen biochemical and mechanical properties and restored osteoblast and endothelial function. These findings underscore
Micaila DE Curtis, Yoontae Kim, Rahul Patil, Xinran Zhang, Meth Jayatilake, Orelle Bulgin, Peter Lialios, Sana Surrency, Soraya Tarrah, Argyris K. Lazaris, Alison Grafton, James Williams IV, Seyedeh Boshra Nouraie, Maria Bizaki, Penelope Xeron, Edward Van Keuren, Jonathan E. Seppala, Evagelia C. Laiakis, Joanna B. Kitlinska, Stella Alimperti   +19 more
wiley   +1 more source

The antiSMASH database, a comprehensive database of microbial secondary metabolite biosynthetic gene clusters

Nucleic Acids Res., 2016
Secondary metabolites produced by microorganisms are the main source of bioactive compounds that are in use as antimicrobial and anticancer drugs, fungicides, herbicides and pesticides. In the last decade, the increasing availability of microbial genomes
K. Blin, M. Medema, R. Kottmann, S. Lee, T. Weber   +4 more
semanticscholar   +1 more source

Evaluation of phenolic profile, antioxidant and anticholinesterase effects of Fuscoporia torulosa

International Journal of Secondary Metabolite, 2019
In this study, we investigated antioxidant and anticholinesterase activities of the hexane, chloroform, acetone, methanol and water extracts of F. torulosa mushroom with total phenolic contents.
Mehmet Emin Emin Duru, Gülsen Tel-Çayan, Ebru Deveci   +2 more
doaj   +1 more source

A Microphysiological Interface of Skeletal Myobundles and Inflamed Adipose Tissue for Recapitulating Muscle Dysfunction in an Obese Microenvironment

Advanced Healthcare Materials, EarlyView.
A human cell‐based microphysiological system integrates engineered muscle tissues with an inflamed adipose–macrophage niche to model obese microenvironment‐induced muscle dysfunction. Muscle contraction is quantified by pillar deflection coupled with computational stiffness estimation. Secretome and transcriptomic profiling reveal inflammation‐mediated
Seunggyu Kim, Tianxin Cao, Zhengpeng Wan, Jaesang Kim, Zhuxuan Li, Legairre A. Radden II, Rakesh Santhanam, Eunkyung Clare Ko, Tatsuya Osaki, Sarah Spitz, Hyunmin Moon, Maria Proestaki, Seokbeom Roh, Gyudo Lee, Jessie S. Jeon, Curtis R. Warren, Roger D. Kamm   +16 more
wiley   +1 more source

Phytochemical Screening of Secondary Metabolites with Antimicrobial Activity from Aspergillus Fumigatus Strain Mf-1

, 2023
Kalyani Pullapukuri
openalex   +1 more source