Results 301 to 310 of about 3,541,226 (351)

Structure, evolution, and roles of MYB transcription factors proteins in secondary metabolite biosynthetic pathways and abiotic stresses responses in plants: a comprehensive review. [PDF]

Front Plant Sci
Ma Z, Hu L, Zhong Y.
europepmc   +1 more source

ATP Hydrolysis by α‐Synuclein Amyloids is Mediated by Enclosing β‐Strand

Advanced Science, EarlyView.
Pathological amyloids have been considered chemically inert until recently. Here it is shown that α‐synuclein amyloids catalyze the hydrolysis of the universal energy molecule, ATP. The cryo‐EM structure of the complex reveals an additional β‐strand (purple) that encloses the ATP‐binding site. Within the cavity, several lysine residues are required for
Lukas Frey, Fiamma Ayelen Buratti, Istvan Horvath, Shraddha Parate, Ranjeet Kumar, Roland Riek, Pernilla Wittung‐Stafshede   +6 more
wiley   +1 more source

Effect of Light Intensity and Light Spectrum of LED Light Sources on Photosynthesis and Secondary Metabolite Synthesis in <i>Ocimum basilicum</i>. [PDF]

Plants (Basel)
Jokic L, Pappert I, Khanh TQ, Kaldenhoff R.   +3 more
europepmc   +1 more source

A chemical analysis of the Pelargonium species: P. odoratissimum, P. graveolens, and P. zonale identifies secondary metabolites with activity against gram-positive bacteria with multidrug-resistance

Diana Celi, E.M. Aranibar Quiroz, Andrea Beltrán-Noboa, António Machado, Eduardo Tejera, Paulina Fernández-Soto   +5 more
openalex   +2 more sources

Neutrophil Extracellular Trap Reprograms Cancer Metabolism to Form a Metastatic Niche Promoting Non‐Small Cell Lung Cancer Brain Metastasis

Advanced Science, EarlyView.
This study mainly combines spatial/single‐cell transcriptomics and metabolomics to reveal LOX+ Malig‐5 as NSCLC brain metastasis‐initiating cells, forming a niche with NET‐releasing neutrophils via the NET‐KRT10 axis. The metastatic niche is involved with metabolic reprogramming, with palmitic acid serving as a key metabolite.
Bo Chen, Karrie M. Kiang, Fangkun Liu, Chuntao Li, Xizhe Li, Chen Weiwei, Xin Fu, Gelei Xiao, Jingyi Sun, Erhan Da, Junbo Liao, Hongshu Zhou, Li Meng, Li Zhou, Tao Song, Longbo Zhang, Gilberto Ka‐Kit Leung, Liyang Zhang   +17 more
wiley   +1 more source

Combining Metal(loid) and Secondary Metabolite Levels in Olea europaea L. Samples for Geographical Identification. [PDF]

Foods
Nardin R, Tamasi G, Baglioni M, Fattori G, Boldrini A, Esposito R, Rossi C.   +6 more
europepmc   +1 more source

Clinically Inspired Multimodal Treatment Using Induced Neural Stem Cells‐Derived Exosomes Promotes Recovery of Traumatic Brain Injury through Microglial Modulation

Advanced Science, EarlyView.
This study explores the therapeutic potential of iNSC‐Exo via local and systemic delivery in TBI mice. It is found that iNSC‐Exo enhances NRXN signaling through Microglia_Nrg3 and Microglia_Rarb, effectively promoting functional and neurological recovery, suggesting a new therapeutic strategy for TBI. Abstract Traumatic brain injury (TBI) poses serious
Jiaojiao Li, Maoxiang Xu, Boyu Cai, Xiangyu Li, Zhanping Liang, Xiaohuan Xia, Haitao Zhang, Zhiwen Zhang, Fei Tan, Jialin Charlie Zheng   +9 more
wiley   +1 more source

Genomic Sequencing and Characterization of Two <i>Auricularia</i> Species from the Qinling Region: Insights into Evolutionary Dynamics and Secondary Metabolite Potential. [PDF]

J Fungi (Basel)
Qi J, Kang S, Zhang M, Qi S, Li Y, Vadim K, Du S, Li M.   +7 more
europepmc   +1 more source

Selected Plant Essential and Seed Oils and their Secondary Metabolites Used as Insecticides: A Review

Banyaladzi Doctor Paphane, Dikabo Mogopodi, Bonang Nkoane, Nyasha Makuve   +3 more
openalex   +2 more sources

cGAS Inhibits ALDH2 to Suppress Lipid Droplet Function and Regulate MASLD Progression

Advanced Science, EarlyView.
cGAS is a cytosolic DNA sensor known for innate immune defense. cGAS binds and suppresses ALDH2 are showed, limiting acetyl‐CoA production. cGAS loss activates ALDH2, promoting histone acetylation, lipogenesis, and lipid droplets accumulation. cGas‐/‐ mice on a high‐fat diet show signs of worsened MASLD.
Ying Wang, Yu Deng, Jianfeng Chen, Quentin Hahn, David S. Umbaugh, Zhigang Zhang, Yanqiong Zhang, Sarah E. Rowe, Lupeng Li, Laura E. Herring, Brian P. Conlon, Edward A. Miao, Blossom Damania, Anna Mae Diehl, Pengda Liu   +14 more
wiley   +1 more source