Results 131 to 140 of about 8,349,404 (268)

Investigation of Complement Activation and Cytokine Signatures in AQP4+ NMOSD, MOGAD, and MS

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Aquaporin‐4‐IgG seropositive neuromyelitis optica spectrum disorder (AQP4+ NMOSD), myelin oligodendrocyte glycoprotein antibody‐associated disease (MOGAD), and multiple sclerosis (MS) are pathophysiologically distinct neuroinflammatory disorders. Complement activation is a major mechanism of injury in AQP4+ NMOSD, whereas its role in
Angeliki G. Filippatou   +23 more
wiley   +1 more source

Culture‐Negative Septic Pulmonary Embolism Secondary to Lower‐Limb Cellulitis Following Recent Dengue Fever Complicated by Hydropneumothorax: A Case Report

open access: yesClinical Case Reports
Secondary bacterial infection and septic pulmonary embolism should be considered in patients recovering from dengue fever who develop focal soft‐tissue infection, respiratory symptoms, or markedly elevated inflammatory markers.
Faiza Arif   +7 more
doaj   +1 more source

The Association of Amyloid‐β and Tau With Synaptic Dysfunction in Alzheimer's Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To clarify the relative contributions of amyloid and tau to synaptic dysfunction in Alzheimer's disease (AD). Methods We included 109 cognitively unimpaired and impaired individuals from the Geneva Memory Center with available CSF synaptic biomarkers (neurogranin, SNAP‐25, GAP‐43). Participants were stratified according to amyloid (A)
Fausto Roveta   +11 more
wiley   +1 more source

Acute Endocrine Alterations After Traumatic Brain Injury and 6‐Month Functional Outcome

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Acute multi‐axis endocrine alterations after traumatic brain injury (TBI) remain incompletely characterized. This study aimed to examine their temporal patterns and explore their associations with 6‐month functional outcome and early inflammatory markers.
Biao Xu   +9 more
wiley   +1 more source

Antipsychotic augmentation with venlafaxine for treatment of negative symptoms in chronic schizophrenia - A case series

open access: yes
Negative symptoms represent a core feature in schizophrenia and the deficit syndrome in chronic schizophrenic patients is closely related to their poor outcome and global failure in community adaptation.
Mukaetova-Ladinska E   +2 more
core   +3 more sources

Stress, Negative Cognitive Style, and Coping as Predictors of Depressive Symptoms in Children of Depressed Parents

open access: yes, 2010
Stress, negative cognitive style, and coping were studied as predictors of depressive symptoms in children and adolescents at risk for depression. This study examined 166 children and adolescents (ages 9 to 15) of depressed parents to understand how ...
Potts, Jennifer Elizabeth
core  

Course of neurological soft signs in first-episode schizophrenia: Relationship with negative symptoms and cognitive performances

open access: yes, 2015
This prospective study examined the course of neurological soft signs (NSS) in patients with first-episode schizophrenia and its relationship with negative symptoms and cognitive functions.
Ho, Karen K. Y.   +8 more
core  

Anorectal Dysfunction in Systemic Sclerosis: Clinical Phenotypes and Functional Patterns

open access: yesArthritis Care &Research, EarlyView.
Objective The aim of this study was to characterize specific physiologic defects in anorectal dysfunction in systemic sclerosis (SSc) using anorectal manometry (ARM), evaluate associations with gastrointestinal (GI) and extraintestinal clinical phenotypes, and explore potential serologic markers for risk stratification.
Timothy Kaniecki   +6 more
wiley   +1 more source

Frailty Predicts Incident Osteoporotic Fractures in Veterans with Rheumatoid Arthritis

open access: yesArthritis Care &Research, EarlyView.
Objective Rheumatoid arthritis (RA) is associated with an increased risk of frailty and osteoporosis, but the relationship between frailty and incident osteoporotic fractures in RA is underexplored. Methods Data were from the Veterans Affairs (VA) Rheumatoid Arthritis Registry. Frailty was measured using the VA Frailty Index (VAFI).
Katherine D. Wysham   +14 more
wiley   +1 more source

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