Results 161 to 170 of about 8,349,404 (268)

Combating Inflammation and Promoting Anabolism in Osteoarthritic Cartilage Defect With an MMP13‐Sensing Dual‐Drug Scaffold

Advanced Science, EarlyView.
ABSTRACT Osteoarthritis (OA) is a widespread degenerative joint condition marked by progressive cartilage breakdown, and a chronic inflammatory microenvironment, where conventional therapies largely fail to halt disease progression. To address this unmet need, an intra‐articularly implantable, disease‐responsive scaffold was developed for combinatorial
Zhen Zhang, Bangheng Liu, Yulei Mu, Huiqun Zhou, Liang Ma, Chenjie Xu, Dong‐An Wang   +6 more
wiley   +1 more source

Does the use of hormonal contraceptives induce negative metacognitions, brooding, and depressive symptoms in an adolescent community sample? [PDF]

Compr Psychoneuroendocrinol
Kennair LEO, Stavang M, Grønnæss I, Myhr HB, Hagen R, Grøntvedt TV, Gangestad SW, Bendixen M.   +7 more
europepmc   +1 more source

Left prefrontal high-frequency rTMS may improve movement disorder in schizophrenia patients with predominant negative symptoms – A secondary analysis of a sham-controlled, randomized multicenter trial

Schizophrenia Research, 2019
Daniel Kamp, Christina Engelke, Thomas Wobrock, Wolfgang Wölwer, Georg Winterer, Christian Schmidt-Kraepelin, Wolfgang Gaebel, Berthold Langguth, Michael Landgrebe, Peter Eichhammer, Elmar Frank, Göran Hajak, Christian Ohmann, Pablo E. Verde, Marcella Rietschel, Ahmed Raees, William G. Honer, Berend Malchow, Thomas Schneider-Axmann, Peter Falkai, Alkomiet Hasan, Joachim Cordes   +21 more
openaire   +4 more sources

Recent Advances in Laser‐Induced Graphene‐Based Gas Sensors: From Sensing Mechanisms to Biomedical Applications

Advanced Science, EarlyView.
Laser‐induced graphene (LIG) provides a scalable, laser‐direct‐written route to porous graphene architecture with tunable chemistry and defect density. Through heterojunction engineering, catalytic functionalization, and intrinsic self‐heating, LIG achieves highly sensitive and selective detection of NOX, NH3, H2, and humidity, supporting next ...
Md Abu Sayeed Biswas, Ankan Dutta, Shuvendu Das, Abu Musa Abdullah, Wanqing Zhang, Fatema Tuz Zohra, Huanyu Cheng   +6 more
wiley   +1 more source

Seronegative End-Stage Type I Achalasia With Megaesophagus in a Middle-Aged Woman From Central America: A Case Report. [PDF]

Cureus
Dominguez DC, Richard J, El-Talla A.
europepmc   +1 more source

Charting Endocrine Progenitors Across Species and Organs

Advanced Science, EarlyView.
Endocrine progenitors give rise to the hormone‐producing cells of the pancreas and intestine. Using single‐cell multiomics and proteomics, this study compares these progenitors across species, systems, and organs, mapping the conserved and species‐specific gene regulatory networks that guide their formation.
Changying Jing, Michael Sterr, Özüm Sehnaz Caliskan, Lama Saber, Nicole Katarina Rogers, Samuel Ogden, Kei Kozawa, Christos Karampelias, Jessica Jaki, Aimée Bastidas‐Ponce, Falk Janos Farkas, Oliver Czarnecki, Osvaldo Rodrigues Pereira, Perla Cota, Valerie Vandenbempt, Diego Balboa, Anika Böttcher, Natalie Krahmer, Mohammad Lotfollahi, Julie B. Sneddon, Heiko Lickert, Mostafa Bakhti   +21 more
wiley   +1 more source

eHealth Literacy and Depressive Symptoms Among Adults Aged 50 Years and Older in China: A National Cross-Sectional Study. [PDF]

Depress Anxiety
Zhou Q, Guo S, Jing R.
europepmc   +1 more source

Disrupted TFEB/GDNF–cAMP/ATP Coupling Underlies Astrocytic Dysfunction and Depression in LRRK2 G2019S Parkinson's Mice

Advanced Science, EarlyView.
ABSTRACT The LRRK2 G2019S mutation, a Parkinson's disease–linked variant, has been associated with depression‐like phenotypes, but mechanisms remain unclear. We chart age‐dependent behavioral changes and astrocyte reactivity in G2019S mice and define a pathway connecting LRRK2 to TFEB/GDNF signaling, cellular energetics, and inflammation.
Longping Yao, Maryam Hatami, Sumeyye Koc, Qing Jiang, Thomas Skutella, Yuanfeng Zhang   +5 more
wiley   +1 more source

Targeted Restoration of the Microbial Tryptophan Oxidative Pathway Ameliorates Autism‐Like Behavioral and Synaptic Deficits

Advanced Science, EarlyView.
ABSTRACT Autism Spectrum Disorder (ASD) is associated with gut microbiota dysbiosis, yet the contribution of specific microbial metabolic pathways remains unclear. Reanalysis of a public ASD cohort revealed reduced functional potential in microbial tryptophan oxidative metabolism.
Rui Guo, Caian He, Xiao Xiao, Jingmeng Li, Zilong Zhang, Ying He, Chuanchuan Wang, Jiale Zhao, Jun Gong, Jiarui Liang, Tian Yuan, Haiting Sun, Xuebo Liu, Chao Gao, Zhigang Liu   +14 more
wiley   +1 more source

Campylobacter jejuni as a Rare Pathogen in CIED Pocket Infections: A Case Report and Literature Review. [PDF]

Am J Case Rep
Barańska-Pawełczak K, Ziaja B, Opara M, Jacheć W.   +3 more
europepmc   +1 more source