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Asian Journal of Psychiatry
Schizophrenia may be diagnosed based on the presence of positive and negative symptoms. However, the underlying pathophysiology of these positive and negative symptoms remains poorly understood. In this study, we used resting-state functional connectivity (rsFC) to evaluate the integrity of neural circuits associated with primary and secondary rewards ...
Jing Shi +9 more
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Schizophrenia may be diagnosed based on the presence of positive and negative symptoms. However, the underlying pathophysiology of these positive and negative symptoms remains poorly understood. In this study, we used resting-state functional connectivity (rsFC) to evaluate the integrity of neural circuits associated with primary and secondary rewards ...
Jing Shi +9 more
openaire +2 more sources
European Neuropsychopharmacology
Oxidative stress is implicated in schizophrenia. Glutathione (GSH), a crucial endogenous antioxidant, is usually reduced in individuals with schizophrenia. GSH and its precursor, N-acetyl cysteine, have demonstrated potential as adjunctive treatment for schizophrenia; however, their effectiveness appears inconsistent, possibly because of their limited ...
Chieh-Hsin Lin, Hsien-Yuan Lane
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Oxidative stress is implicated in schizophrenia. Glutathione (GSH), a crucial endogenous antioxidant, is usually reduced in individuals with schizophrenia. GSH and its precursor, N-acetyl cysteine, have demonstrated potential as adjunctive treatment for schizophrenia; however, their effectiveness appears inconsistent, possibly because of their limited ...
Chieh-Hsin Lin, Hsien-Yuan Lane
openaire +2 more sources
Distinguishing Change in Primary and Secondary Negative Symptoms
American Journal of Psychiatry, 1999G, Remington, S A, Chong, S, Kapur
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L'Encephale, 2001
Negative symptoms in schizophrenia represent a diagnostic and therapeutic challenge. Diagnostically, they need to be differentiated from depression and treatment-related variables. The latter include akinesia, a part of drug-induced Parkinsonism, sedation, and effects of understimulation, as they have been reported in patients institutionalised for ...
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Negative symptoms in schizophrenia represent a diagnostic and therapeutic challenge. Diagnostically, they need to be differentiated from depression and treatment-related variables. The latter include akinesia, a part of drug-induced Parkinsonism, sedation, and effects of understimulation, as they have been reported in patients institutionalised for ...
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The course of primary and secondary negative symptoms in a controlled trial with olanzapine
Schizophrenia Research, 1996Gary D. Tollefson +2 more
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European Archives of Psychiatry and Clinical Neuroscience, 2017
Stefan Priebe, Mark Savill, Aida Farreny
exaly
Stefan Priebe, Mark Savill, Aida Farreny
exaly