Results 201 to 210 of about 2,724,238 (249)

Virtual cell construction for artificial intelligence‐driven drug discovery

open access: yesBritish Journal of Pharmacology, EarlyView.
Cells are the fundamental units through which genetic variation and pharmacological perturbations influence disease processes and therapeutic responses. However, cellular responses to intervention are strongly shaped by biological context, creating a central challenge for drug discovery: predicting how specific perturbations reshape cellular systems ...
Yuran Jia   +5 more
wiley   +1 more source

Measuring Lead Userness: Development and Validation of a Hierarchical Scale

open access: yesCreativity and Innovation Management, Volume 34, Issue 4, Page 944-962, December 2025.
ABSTRACT Lead user theory has gained traction in both academia and practice, given that involving lead users (LUs) can yield more innovative and commercially successful products. Yet, measurement inconsistencies have hindered consensus on how to reliably assess lead userness.
Moritz Paulus   +3 more
wiley   +1 more source

Standards for accreditation, secondary schools

open access: yes, 1971
Northwest Association of Secondary and Higher Schools. Secondary Commission
core   +1 more source

A Collective Approach to Creative Entrepreneurship: Evidence From Performing Arts Incubators

open access: yesCreativity and Innovation Management, EarlyView.
ABSTRACT Although the concept of artists as creative entrepreneurs has been studied to enable artists to survive in uncertain environments, some studies have criticized this approach for focusing on individual artists, which may lead to isolation and jeopardize their careers.
Julia Parigot, Emmanuel Coblence
wiley   +1 more source

TERT Promoter Mutations Are Preferentially Associated With the ERBB2 G776‐Altered Subtype of HER2‐Mutant NSCLC

open access: yesCancer Science, EarlyView.
A two‐stage clinicogenomic analysis identified and independently validated a preferential association between TERT promoter mutations and the ERBB2 G776‐altered subtype of HER2‐mutant NSCLC, highlighting subtype‐specific genomic heterogeneity. ABSTRACT HER2‐mutant non‐small cell lung cancer (NSCLC) comprises molecularly heterogeneous tumors with ...
Akihiro Yoshimura   +3 more
wiley   +1 more source

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