Results 81 to 90 of about 2,724,238 (249)

TSTScope Unifies Single‐Cell Multi‐Omics to Identify Functional T Cell States Predictive of Immunotherapy Response

open access: yesAdvanced Science, EarlyView.
TSTScope is an interpretable AI framework that integrates single‐cell transcriptomes with TCR information through curated gene‐program constraints. By linking receptor context to functional T cell states, it reveals response‐associated tumor‐specific T cell programs in lung cancer immunotherapy cohorts and defines an MPR score associated with ...
Shiwei Cao   +8 more
wiley   +1 more source

EUPHEMISMS AS A TYPE OF SECONDARY NOMINATION

open access: yes
Secondary nomination refers to the process of indirect naming, where a term is used to replace another, often to mitigate its harshness or to avoid taboos. Euphemisms are a key example of this phenomenon, serving as polite or softer alternatives to terms that could be perceived as offensive, crude, or unpleasant.
openaire   +2 more sources

Nomination, Dé-nomination, Re-nomination

open access: yes, 2004
Thomas Joan. Nomination, Dé-nomination, Re-nomination. In: Onomastique et patrimoine. Actes du Colloque d’onomastique du Teich (septembre 2003) Paris : Société française d'onomastique, 2004. pp. 321-326.
Thomas, Joan
core  

VlPAG/DRN Microglia Drive Neuropathic Pain‐Induced Depression via a Defined Neuroimmune Axis

open access: yesAdvanced Science, EarlyView.
Peripheral nerve injury (SNI) induces neuropathic pain, activates midbrain microglia, and triggers an NLRP3–IL‐1β–dependent inflammatory cascade. IL‐1β signals through IL‐1R1 on vlPAG/DRN VGLUT2+ neurons (vlPAG/DRNGlu), inducing hyperexcitability and driving the vlPAG/DRNGlu→BNSTGABA circuit to produce the affective component of neuropathic pain ...
Jing Yang   +7 more
wiley   +1 more source

Multi‐Omics Integration Identifies a CDH3‐Associated Malignant Epithelial State and Immunosuppressive Niche to Predict Prognosis in Thymic Epithelial Tumors

open access: yesAdvanced Science, EarlyView.
Single‐cell, spatial, molecular, and pathology analyses identify a CDH3‐associated malignant epithelial state in thymic epithelial tumors. This state links stem‐like and EMT programs to M2 macrophage–rich immunosuppressive niches, genomic instability, poor survival, and drug vulnerability.
Yuntao Feng   +13 more
wiley   +1 more source

Grammatical and Semantic Word-Formation of Toponymic Derivatives (on the Material of the Toponym “CИБИPЬ”)

open access: yesSHS Web of Conferences, 2018
The paper presents morphemic-derivational structure of toponymic derivatives (toponymy-derived formations) of proper name “Cибирь”. In revealed derived words authors identify morphemes, specify the methods of their production, provide statistics on word ...
Litovkina Anna M.
doaj   +1 more source

Lactate‐Induced K370 Lactylation of STING Inhibits STING‐TBK1 Signaling and Dampens Anti‐Tumor Immunity

open access: yesAdvanced Science, EarlyView.
Lactate accumulation in glioblastoma drives lactylation of STING at lysine 370, a primate‐conserved residue. K370 lactylation weakens STING‐TBK1 binding, destabilizes STING, and disrupts ER‐to‐Golgi trafficking, blunting type I interferon signaling. LDHA inhibition reverses K370 lactylation and improves the antitumor efficacy of STING agonism combined ...
Yueyao Wu   +11 more
wiley   +1 more source

Secondary nomination as a method of formation ofnew terminology units in banking and exchange terminology.

open access: yes, 2011
У статті досліджується вторинна номінація як спосіб утворення нових термінологічних одиниць у банківській і біржовій термінології, також аналізується структура вторинно номінованих термінів і робиться висновок про спадковість інформації у вторинній ...
Rumiantseva, Olena A.   +2 more
core   +1 more source

VISUALIZATION OF THE ARTISTIC IMAGE OF WAR IN CONTEMPORARY UKRAINIAN POETRY (BASED ON THE MATERIAL OF THE ANTHOLOGY «WITH FAITH IN VICTORY»)

open access: yesВісник Харківського національного університету імені В.Н. Каразіна. Серия: Теорія культури та філософіі науки
The article is devoted to the analysis of artistic means of visualizing the image of war in modern Ukrainian poetry based on the material of the anthology "With Faith in Victory" (Kharkiv: Maidan, 2024), while considering the peculiarities of the ...
Yuliya Solovyova   +3 more
doaj   +1 more source

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