Results 81 to 90 of about 4,266 (303)

CHCHD10 Mitigates Alzheimer's Disease‐Related Phenotypes in Association With Epigenetic Remodeling in Directly Reprogrammed Neurons

Advanced Science, EarlyView.
CHCHD10 loss in Alzheimer's disease is associated with mitochondrial dysfunction, epigenomic disruption, and tau pathology. Restoration of CHCHD10 shifts DNA methylation toward a non‐disease state and reduces tau and amyloid pathology, with KATNAL2 acting as a downstream effector.
Teresa M. Thomas, Ching‐Yao Yang, Kexin Zhang, Liam Wetzel, Dina Bugybayeva, Julia Ferguson, Md Mahmudul Hasan, William Samsa, Nandita Patil, Anshul Dash, Tarini Gowda, Xiongwei Zhu, Feixiong Cheng, Tian Liu   +13 more
wiley   +1 more source

Naprâmki onovlennâ prikmetnikovoï leksiki v sučasnih zmì [PDF]

, 2021
The article reveals the directions of updating adjective vocabulary in modem media, the influence of extralinguistic factors on the choice and implementation of wordformation resources of modem Ukrainian nomination of adjective derivatives.
Vekua Natalia
core  

Targeting WDR12 Unleashes T‐Cell‐Mediated Antitumor Activity in Melanoma by Destabilizing CD276

Advanced Science, EarlyView.
WDR12 cooperates with the chaperonin subunit CCT7 to maintain CD276 stability on tumor cells, suppressing T‐cell activity and promoting immune escape. SU14813, a small‐molecule WDR12 inhibitor, reduces CD276 stability and relieves CD276‐mediated T‐cell suppression.
Jie Pan, Ruimin Chang, Meng Zhang, Qian Dong, Guanxiong Zhang, Xiang Chen, Mingliang Chen, Lixia Lu, Xiaowei Liang, Yeye Guo, Juan Su   +10 more
wiley   +1 more source

Models of Metaphorical Nomination of Nouns Denoting Persons in the Russian and Bulgarian Languages

, 2015
The article describes the main models of metaphorical nomination of nouns denoting persons in the Russian and Bulgarian languages in the latest period.
Ivanova, Vanya
core   +1 more source

Participatory Policy Development: Reflections on Designing the Strong Roots for Our Futures Program in Victoria

Australian Journal of Social Issues, EarlyView.
ABSTRACT In this paper, we trace the journey to create the Strong Roots for our Futures Program, a government program to resource and support Traditional Owners to undertake a range of activities in areas where no state recognition existed. We provide a background to state recognition in Victoria before considering the program design, leading to an ...
Nell Reidy, Bhiamie Williamson, Jesse Williams   +2 more
wiley   +1 more source

Caregiver Reports on the Needs and Experiences of Children Impacted by Parental Incarceration: Results From an Australian Survey

Australian Journal of Social Issues, EarlyView.
ABSTRACT Children experiencing parental imprisonment are known to be among the most overlooked in our community. They often experience multiple and compounding disadvantages, with long‐term consequences, but receive no specialised assistance. Knowledge about these children and their families is lacking in Australia and is required to inform policy ...
Catherine Flynn, Lana Battaglia, Lorana Bartels, Susan Dennison, Susy Harrigan, Lee Huggins, Sofia Grage‐Moore   +6 more
wiley   +1 more source

Grammatical and Semantic Word-Formation of Toponymic Derivatives (on the Material of the Toponym “CИБИPЬ”)

SHS Web of Conferences, 2018
The paper presents morphemic-derivational structure of toponymic derivatives (toponymy-derived formations) of proper name “Cибирь”. In revealed derived words authors identify morphemes, specify the methods of their production, provide statistics on word ...
Litovkina Anna M.
doaj   +1 more source

Secondary nomination of emotionally-charged vocabulary (based on Russian and English common somatisms)

, 2018
В статье рассматриваются способы вторичной номинации эмоционально-окрашенной лексики, обозначающей части тела человека «голова», «лицо», «нос», «рот» в русском и английском языках; анализируются случаи совпадения номинаций в двух языках, а также ...
Осипова, О. П.
core  

Nothing to See Here: Researching Non‐Recent Child Abuse in Schools and the Politics of Silence

Australian Journal of Social Issues, EarlyView.
ABSTRACT While institutions, including schools, have responsibilities to protect children from harm, responses to instances of child sexual abuse have often exhibited avoidance and denial. Recent public inquiries in Australia revealed that some institutions, particularly in the Catholic sector, employed a deliberate strategy of silence which was used ...
John Crowley, Katie Wright, Kate O'Connor   +2 more
wiley   +1 more source

VISUALIZATION OF THE ARTISTIC IMAGE OF WAR IN CONTEMPORARY UKRAINIAN POETRY (BASED ON THE MATERIAL OF THE ANTHOLOGY «WITH FAITH IN VICTORY»)

Вісник Харківського національного університету імені В.Н. Каразіна. Серия: Теорія культури та філософіі науки
The article is devoted to the analysis of artistic means of visualizing the image of war in modern Ukrainian poetry based on the material of the anthology "With Faith in Victory" (Kharkiv: Maidan, 2024), while considering the peculiarities of the ...
Yuliya Solovyova, Maryna Konieva, Sofiia Konavalova, Nataiia Markhaichuk   +3 more
doaj   +1 more source