Results 131 to 140 of about 26,876 (262)

Secondary Stroke Prevention in Atrial Fibrillation [PDF]

, 2000
Andrew Evans, Iñigo Perez, Gloria Yu, Lalit Kalra   +3 more
openalex   +1 more source

Overexpression of CDT1 inhibits cell cycle progression at S phase by interacting with the mini‐chromosome maintenance complex and causes DNA damage

FEBS Open Bio, EarlyView.
CDT1 is an essential protein for DNA replication licensing that loads the MCM complex, the eukaryotic replicative DNA helicase, onto replication origins. Overexpression of CDT1 induces cell cycle arrest at the S phase. Here we showed CDT1 inhibits the progression of replication forks by interacting with the MCM complex, leading to the stalling and ...
Takashi Tsuyama, Nonoka Takayama, Rina Tanaka, Yuuki Arai, Yohko Yamaguchi, Yuko Nawata, Yutaro Azuma, Shusuke Tada   +7 more
wiley   +1 more source

Secondary Prevention Antibiotic Treatment Trials for Coronary Artery Disease [PDF]

, 2000
J. Thomas Grayston
openalex   +1 more source

HSP70 governs permeability and mechanotransduction in primary human endothelial cells

FEBS Open Bio, EarlyView.
HSP70 chemical inhibition reduces endothelial cell proliferation and increases permeability, the latter supported by normal interendothelial junctional protein distribution. HSP70 also plays a role in shear stress response, a hemodynamic force naturally present in blood vessels and correlated with vessel protection.
Andrea Pinto‐Martinez, Everton G. Melo, Isadora C. B. Pavan, Percíllia V. S. Oliveira, Luiza B. C. T. Coimbra, Thaís L. S. Araujo   +5 more
wiley   +1 more source

Should lipid-lowering drugs be part of initial therapy in the secondary prevention of CHD?

, 1996
Christie M. Ballantyne, M. Stewart West, Suzanne M. Jaax, Lynne W. Scott, J. Alan Herd, Peter H. Jones, John A. Farmer, Antonio M. Gotto   +7 more
openalex   +1 more source

Molecular determinants of signal transduction in tropomyosin receptor kinases

FEBS Open Bio, EarlyView.
Tropomyosin receptor kinases control critical neuronal functions, but how do the same receptors produce diverse cellular responses? This review explores the structural mechanisms behind Trk signaling diversity, focusing on allosteric modulation and ligand bias.
Giray Enkavi
wiley   +1 more source

Role of secondary prevention in congestive heart failure due to coronary artery disease

, 1998
Robert D. Brook, Philip Greenland
openalex   +1 more source

Secondary Prevention of Coronary Heart Disease [PDF]

, 2000
Steven M. Haffner
openalex   +1 more source

ATG4B is required for mTORC1‐mediated anabolic activity and is associated with clinical outcomes in non‐small cell lung cancer

FEBS Open Bio, EarlyView.
The relationship between anabolic and catabolic processes governing lung cancer cell growth is nuanced. We show that ATG4B, an autophagy regulator, is elevated in lung cancer and that high ATG4B is associated with worse patient outcomes. Targeting ATG4B in cells reduces growth, protein synthesis, and mTORC1 activity, demonstrating a new relationship ...
Patrick J. Ryan, Bethany C. Guerra, Selina Uranga, Jessica M. Cardin, Steven E. Riechman, Mariana Janini Gomes, James D. Fluckey   +6 more
wiley   +1 more source

Association of Previous Myocardial Infarction and Time to Presentation With Suspected Acute Myocardial Infarction

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2021
Valentina Troester, Ivo Strebel, Thomas Nestelberger, Jasper Boeddinghaus, Maria Rubini Gimenez, Pedro Lopez‐Ayala, Luca Koechlin, Noemi Glarner, Alexandra Prepoudis, Òscar Miró, F. Javier Martin‐Sanchez, Damian Kawecki, Dagmar I. Keller, Raphael Twerenbold, Christian Mueller   +14 more
doaj   +1 more source