Results 161 to 170 of about 4,919,522 (294)

Primary and secondary prevention of cervical cancer during the COVID-19 pandemic in Sao Paulo State, Brazil. [PDF]

Rev Inst Med Trop Sao Paulo
Carvalho TS, Ferreira MA, Geber Júnior JC, Lorente S, Maciel CD, Duarte-Neto AN.   +5 more
europepmc   +1 more source

The C‐terminal truncated splicing variant of NK1R negatively modulates substance P‐stimulated NK1R signaling

FEBS Open Bio, EarlyView.
The neurokinin 1 receptor exists as full‐length (NK1L) and C‐terminally truncated (NK1S) splice variants. We show that NK1S heterodimerizes with NK1L, impairing Gαq coupling and Ca2+ mobilization while enhancing β‐arrestin1 recruitment. NK1S suppresses substance P‐driven gene expression and cell migration, revealing NK1S as an endogenous biased ...
Lan Phuong Nguyen, Duc Trung Nguyen, Minyoung Cho, Jihun Kim, Soyeon In, Thai Uy Nguyen, Sunghoon Hurh, Beom Jin Park, Jong‐Ik Hwang   +8 more
wiley   +1 more source

Secondary prevention lipid management after ACS at a DGH: a quality improvement project. [PDF]

Br J Cardiol
Laird M, Tang PT, Patel M, Hyde T.
europepmc   +1 more source

Genetic dissection of human ABCE1 in yeast reveals separable requirements for ribosome recycling and suppression of aberrant reinitiation

FEBS Open Bio, EarlyView.
Human ABCE1 cannot functionally replace its yeast ortholog. Yeast–human chimera analysis identified NBD1 as a major interspecies barrier. Genetic screening yielded hABCE1 revertants that rescue yeast viability but fail to suppress aberrant translation reinitiation in the 3′ UTR.
Eriko Nakata, Yuxin Li, Kei Endo, Koichi Ito   +3 more
wiley   +1 more source

Pelacarsen and lipoprotein(a) apheresis in secondary prevention: the Lp(a)FRONTIERS APHERESIS trial. [PDF]

Eur Heart J
Parhofer KG, Julius U, Herzog AL, Krüger T, Weinmann-Menke J, Heine GH, Cao H, Schorr J, Ferber P, Wang J, Cristante E, Müller-Edenborn B, Vogt A, Schettler V, Steinhagen-Thiessen E.   +14 more
europepmc   +1 more source

Type I interferons modulate autophagy to shape gemcitabine response in pancreatic cancer cells

FEBS Open Bio, EarlyView.
Type I interferons differentially modulate autophagy and the response of pancreatic cancer cells to gemcitabine. IFNα2b stimulates autophagic flux and protects cells from gemcitabine‐induced cell death, contributing to chemoresistance. In contrast, IFNβ1a inhibits autophagosome formation and enhances gemcitabine‐induced cell death, resulting in ...
Lucy E. Bonilla, Martín M. Ledesma, Santiago A. Behr, Matías A. Pibuel, María L. Palanek, Daniel H. Grasso, Maria N. Garcia, Juan Garona, Silvina L. Lompardía, Elida Álvarez, Daniela L. Papademetrio   +10 more
wiley   +1 more source

Bempedoic Acid in Secondary Prevention

American Journal of Preventive Cardiology
Idine Mousavi, Vijay Nambi, Layla A. Abushamat, Sadeer G. Al-Kindi, Michael D. Shapiro, Laurence Sperling, Salim S. Virani, Abdul Mannan Khan Minhas   +7 more
doaj   +1 more source

Retraction: Case-control study to develop and validate a questionnaire for the secondary prevention of endometriosis. [PDF]

PLoS One
PLOS One Editors.
europepmc   +1 more source

Identification and characterization of a gene conferring stress resistance in Escherichia coli and cyanobacteria

FEBS Open Bio, EarlyView.
Functional screening identified PcSyn14890, a cyanobacteria‐specific protein that enhances growth and stress resistance in E. coli and Synechocystis PCC6803. Although we expected it to function as a molecular chaperone, it was unable to protect against thermal aggregation of GAPDH.
Akiyo Yamada, Takaaki Tanaka, Manaka Uehara, Keigo Nakano, Ken Morishima, Rintaro Inoue, Masaaki Sugiyama, Masafumi Yohda   +7 more
wiley   +1 more source

Patient-centred treatment failure and secondary prevention after Bascom I for pilonidal sinus disease. [PDF]

Colorectal Dis
Mei Z, Du P, Wang Q.
europepmc   +1 more source