Results 91 to 100 of about 629,418 (288)

Representations of leadership within a gender perspective among secondary school students

Formazione & Insegnamento, 2013
This work focuses on the analysis of the attitudes of young people towards leadership with a view to gender, with the aim of investigating some cultural implicits that can influence the future choices of students and which, precisely for this reason ...
Elena Luppi
doaj  

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Learning with Multiple Representations: Infographics as Cognitive Tools for Authentic Learning in Science Literacy | Apprendre avec des représentations multiples: l'infographie de presse comme outil cognitif pour l'apprentissage authentique en science

Canadian Journal of Learning and Technology, 2018
This paper presents a descriptive case study where infographics—visual representation of data and ideas—have been used as cognitive tools to facilitate learning with multiple representations in the context of secondary school students’ science news ...
Engida Gebre
doaj   +1 more source

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

FEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas, Porter L. Tomsick, Alicia M. Pickrell, Paul D. Morton   +3 more
wiley   +1 more source

Pairwise visual comparison of small RNA secondary structures with base pair probabilities

BMC Bioinformatics, 2019
Background Predicted RNA secondary structures are typically visualized using dot-plots for base pair binding probabilities and planar graphs for unique structures, such as the minimum free energy structure.
Serge Léger, Maria Beatriz Walter Costa, Dan Tulpan   +2 more
doaj   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

FEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa, Akira Hattori, Masafumi Tsujimoto, Toshihide Kobayashi   +3 more
wiley   +1 more source

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

FEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga, Toshiki Takahashi, Akiko Kuma, Hiroyuki Kawahara   +3 more
wiley   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

Aportes al estudio de las representaciones sociales del trabajo y del estudio en jóvenes de distintos niveles de escolaridad media Contributions to the study of social representations of work and study made by youths studying different levels of secondary school

Anuario de Investigaciones, 2009
El proyecto de investigación "Representaciones Sociales del trabajo y del estudio en jóvenes de distintos niveles de escolaridad de la Escuela Media" (Programación Científica 2008-2010 UBACyT) se plantea describir las representaciones sociales del ...
Gabriela Aisenson, Leandro Legaspi, Viviana Valenzuela, Lorena Duro, Romina Celeiro, Virginia Inaebnit, Mariana De Marco, Yamila Pereda   +7 more
doaj  

Intervention Program on Adolescent's Creativity Representations and Academic Motivation

Paidéia (Ribeirão Preto), 2015
Creativity and its promotion are widespread concerns in education. However, few efforts have been made to implement intervention programs designed to promote creativity and other related aspects (e.g., academic motivation).
Maria de Fátima Morais, Saul Neves de Jesus, Ivete Azevedo, Alexandra M. Araújo, João Viseu   +4 more
doaj   +1 more source