Results 31 to 40 of about 3,992,722 (261)

Transcriptome‐wide analysis of circRNA and RBP profiles and their molecular relevance for GBM

open access: yesMolecular Oncology, EarlyView.
CircRNAs are differentially expressed in glioblastoma primary tumors and might serve as therapeutic targets and diagnostic markers. The investigation of circRNA and RNA‐binding proteins (RBPs) interactions shows that distinct RBPs play a role in circRNA biogenesis and function.
Julia Latowska‐Łysiak   +14 more
wiley   +1 more source

Escape from TGF‐β‐induced senescence promotes aggressive hallmarks in epithelial hepatocellular carcinoma cells

open access: yesMolecular Oncology, EarlyView.
Chronic TGF‐β exposure drives epithelial HCC cells from a senescent state to a TGF‐β resistant mesenchymal phenotype. This transition is characterized by the loss of Smad3‐mediated signaling, escape from senescence, enhanced invasiveness and metastatic potential, and upregulation of key resistance modulators such as MARK1 and GRM8, ultimately promoting
Minenur Kalyoncu   +11 more
wiley   +1 more source

Riverside Secondary School Yearbook 1960-1961 [PDF]

open access: yes, 1961
Yearbook of Riverside Secondary School (Windsor, Ontario); also called the Rebelogue.https://scholar.uwindsor.ca/essexcountyontariohighschoolyearbooks/1103/thumbnail ...
Riverside Secondary School (Windsor, Ontario)
core   +1 more source

Interplay of integrins and selectins in metastasis

open access: yesMolecular Oncology, EarlyView.
Here we review the role of integrins and their interplay with selectins in metastasis. The efficacy of integrin‐targeted therapies may be reduced in tumors where metastasis relies heavily on selectins. In certain tumors, integrins and selectins exhibit a synergistic interaction during intraperitoneal dissemination.
Diana Maltseva   +2 more
wiley   +1 more source

Riverside Secondary School Yearbook 1954-1955 [PDF]

open access: yes, 1955
Yearbook of Riverside Secondary School (Windsor, Ontario); also called the Rebelogue; has some minor damagehttps://scholar.uwindsor.ca/essexcountyontariohighschoolyearbooks/1191/thumbnail ...
Riverside Secondary School (Windsor, Ontario)
core   +1 more source

Inhibitor of DNA binding‐1 is a key regulator of cancer cell vasculogenic mimicry

open access: yesMolecular Oncology, EarlyView.
Elevated expression of transcriptional regulator inhibitor of DNA binding 1 (ID1) promoted cancer cell‐mediated vasculogenic mimicry (VM) through regulation of pro‐angiogenic and pro‐cancerous genes (e.g. VE‐cadherin (CDH5), TIE2, MMP9, DKK1). Higher ID1 expression also increased metastases to the lung and the liver.
Emma J. Thompson   +11 more
wiley   +1 more source

Riverside Secondary School Yearbook 1959-1960 [PDF]

open access: yes, 1960
Yearbook of Riverside Secondary School (Windsor, Ontario); also called the Rebelogue.https://scholar.uwindsor.ca/essexcountyontariohighschoolyearbooks/1102/thumbnail ...
Riverside Secondary School (Windsor, Ontario)
core   +1 more source

MET and NF2 alterations confer primary and early resistance to first‐line alectinib treatment in ALK‐positive non‐small‐cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Alectinib resistance in ALK+ NSCLC depends on treatment sequence and EML4‐ALK variants. Variant 1 exhibited off‐target resistance after first‐line treatment, while variant 3 and later lines favored on‐target mutations. Early resistance involved off‐target alterations, like MET and NF2, while on‐target mutations emerged with prolonged therapy.
Jie Hu   +11 more
wiley   +1 more source

Riverside Secondary School Yearbook 1964-1965 [PDF]

open access: yes, 1965
Yearbook of Riverside Secondary School (Windsor, Ontario); also called the Rebelogue.https://scholar.uwindsor.ca/essexcountyontariohighschoolyearbooks/1107/thumbnail ...
Riverside Secondary School (Windsor, Ontario)
core   +1 more source

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