Results 101 to 110 of about 1,592,250 (363)

The role of lipid metabolism in neuronal senescence

open access: yesFEBS Open Bio, EarlyView.
Disrupted lipid metabolism, through alterations in lipid species or lipid droplet accumulation, can drive neuronal senescence. However, lipid dyshomeostasis can also occur alongside neuronal senescence, further amplifying tissue damage. Delineating how lipid‐induced senescence emerges in neurons and glial cells, and how it contributes to ageing and ...
Dikaia Tsagkari   +2 more
wiley   +1 more source

Economics, business and enterprise education: a summary of inspection evidence; April 2007 to March 2010 [PDF]

open access: yes, 2011
This report evaluates the strengths and weaknesses in economics, business and enterprise education in primary schools, secondary schools and colleges. It covers two separate aspects of the curriculum: •formally assessed economics and business courses

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Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

open access: yesFEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li   +8 more
wiley   +1 more source

The Formation of School Peer Groups: Pupils’ Transition from Primary to Secondary School in England [PDF]

open access: yes
This paper examines the transitions from primary to secondary school for a contemporary cohort of children moving between state schools in England. It uses data on over 12,000 primary schools, over 2000 secondary schools and around 400,000 pupils.
Carol Propper   +4 more
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Erythropoietin modulates hepatic inflammation, glucose homeostasis, and soluble epoxide hydrolase and epoxides in high‐fat diet‐induced obese mice

open access: yesFEBS Open Bio, EarlyView.
Erythropoietin administration suppresses hepatic soluble epoxide hydrolase (sEH) expression, leading to increased CYP‐derived epoxides. This is associated with a shift in hepatic macrophage polarization characterized by reduced M1 markers and increased M2 markers, along with reduced hepatic inflammation, suppressed hepatic lipogenesis, and attenuated ...
Takeshi Goda   +12 more
wiley   +1 more source

Are Schools Drifting Apart? Intake Stratification in English Secondary Schools [PDF]

open access: yes
The issue of social segregation in schools has seen a recent resurgence of interest - in the US, UK and internationally - as the debate rages on about whether policies that expand families' freedom to choose amongst schools encourage divergence or ...
Shqiponja Telhaj, Steve Gibbons
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Applicability of mitotic figure counting by deep learning: a development and pan‐cancer validation study

open access: yesFEBS Open Bio, EarlyView.
In this study, we developed a deep learning method for mitotic figure counting in H&E‐stained whole‐slide images and evaluated its prognostic impact in 13 external validation cohorts from seven different cancer types. Patients with more mitotic figures per mm2 had significantly worse patient outcome in all the studied cancer types except colorectal ...
Joakim Kalsnes   +32 more
wiley   +1 more source

The Secondary School.

open access: yesJournal of Educational Sociology, 1940
"Selected references" at end of each chapter except the first. ; Mode of access: Internet.
openaire   +1 more source

General Senior Secondary Education Financing in Indonesia [PDF]

open access: yes, 2013
This report examines the policy options and financial implications of the expansion of senior secondary education in Indonesia. The government wishes to increase the gross enrolment rate from 70% to 85% by 2014 and aims for universal 12-year education by
Edy Priyono, Vita Febriany
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