Results 41 to 50 of about 1,592,250 (363)
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
FEBS Letters, EarlyView.Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
The Present Status of Computers in Secondary Schools in Saudi Arabia [PDF]
Journal of Islamic Studies, 2002 Only few years ago the Ministry of Education started to provide intermediate and secondary schools with computer hardware and software. In addition to this, it started a new program by establishing two courses for secondary schools, The Ministry of ...
Abdulaziz M. Al-Ageely
doaj
Coopération inter-établissements et développement professionnel des enseignants à Shanghai
Revue Internationale d’Éducation de Sèvres, 2022 Preschools, primary and secondary schools in Shanghai are collaborating to promote projects and conduct joint research with the help of renowned teachers and institutions.
Ren Jié
doaj +1 more source
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
FEBS Letters, EarlyView.Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
IL in secondary school [Information literacy in secondary school]
, 2021 It is not clear which is the proper age for a student to start learning knowledge and skill in the information literacy field. In our high school, with young learners from 11 to 18 years old, the target of our efforts is the second grade, with ages between 13 and 14.
openaire +2 more sources
Extra-curricular activities in secondary schools [PDF]
, 1924 Thesis (M.A.)--Boston ...
Robinson, Charles Marshall
core +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
FEBS Letters, EarlyView.We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
Cahiers de la Recherche sur l'Education et les Savoirs, 2017 To improve school infrastructure on Tanzanian territory and increase access to secondary education, the government launched an education development program in 2004.
Nathalie Bonini
doaj +1 more source
PICALM::MLLT10 translocated leukemia
FEBS Letters, EarlyView.This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen +7 more
wiley +1 more source