Results 61 to 70 of about 7,844,407 (352)

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

Les écoles secondaires communautaires en Tanzanie : piliers d’une réforme égalitaire ou éducation de seconde zone ?

open access: yesCahiers de la Recherche sur l'Education et les Savoirs, 2017
To improve school infrastructure on Tanzanian territory and increase access to secondary education, the government launched an education development program in 2004.
Nathalie Bonini
doaj   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

the prevalence of dental crossbite in students of secondary schools of Kerman city in 1994-95 [PDF]

open access: yesJournal of Kerman University of Medical Sciences, 1997
crossbite is a term used to indicate an abnormal buccolingual (labiolingual) relationship of the teeth and can results in unfavorable effects when it is left untreated.the last growth spurt which occurs about the age of 11-12 years in females and 14-15 ...
B.A Ramazanzadeh, K Laghaei
doaj  

Digital libraries at home and abroad for the needs of instruction in the school library

open access: yesKnjižnica, 2001
The authors describe some cases and indicate some possible uses of digital libraries (some of them can also be examples of their construction) for educational purposes, at home and abroad.
Zdenka Verlič
doaj   +1 more source

Factors Influencing Teachers’ Use of Multimedia Enhanced Content in Secondary Schools in Tanzania

open access: yes, 2016
Tanzania is faced with a severe shortage of qualified in-service school science and mathematics teachers. While science and mathematics account for 46% of the curriculum, only 28% of teachers are qualified to teach these subjects.
J. Mtebe, Betty Mbwilo, M. Kissaka
semanticscholar   +1 more source

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

open access: yesFEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas   +3 more
wiley   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

open access: yesFEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa   +3 more
wiley   +1 more source

Leadership Styles and Teachers' Job Satisfaction in Tanzanian Public Secondary Schools

open access: yes, 2016
This study explores the relationship between leadership styles applied by school heads and teachers' job satisfaction in Tanzanian secondary schools. Using a questionnaire, data in this study was collected from 180 teachers in ten secondary schools in ...
Fabian W. Nyenyembe   +3 more
semanticscholar   +1 more source

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

open access: yesFEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga   +3 more
wiley   +1 more source

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