Results 71 to 80 of about 7,844,407 (352)

‘Of course we must be equal, but …’: imagining gendered futures in two rural Southern African secondary schools [PDF]

open access: yes, 2002
Based on focus group discussions held with students at rural secondary schools in Lesotho and Zimbabwe, this paper argues that secondary schools provide important spaces for the (re)construction of gendered identities among rural girls in southern Africa.
Ansell, N
core   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

open access: yesMolecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee   +8 more
wiley   +1 more source

Informal violence in secondary schools [PDF]

open access: yesSinteze, 2016
Various forms of formal and informal violence can be found in secondary schools. Situations in which only one form of violence is present are rare; informal violence often preceds various forms of formal violence and the other way round.
Mikanović Brane R., Maran Marijana M.
doaj  

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Gender imbalance in secondary schools [PDF]

open access: yesForced Migration Review, 2005
Significantly fewer girls than boys attend schools inrefugee camps. As the level of education increases, there is a corresponding decrease in the numbers of female participants. This has resulted in a severe gender imbalance in refugee secondary schools.
Catherine Howgego Mugisha
doaj  

Destinations of leavers from Scottish schools : 1997-1998 to 1999-2000 [PDF]

open access: yes, 2000
"This is a new bulletin providing information about the destinations of leavers from Scottish schools. The information in this publication was previously supplied in a report entitled ‘Leaver Destinations from Scottish Secondary Schools‘ which was ...

core  

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

The effect of student-perceived teacher support on math anxiety: chain mediation of teacher–student relationship and math self-efficacy

open access: yesFrontiers in Psychology
IntroductionThis study investigates the mechanisms linking students’ perceived teacher support with math anxiety, focusing on the mediating roles of the teacher–student relationship and mathematics self-efficacy.MethodsThe research was conducted with 401
Chao Wang   +4 more
doaj   +1 more source

Language Awareness in Italian Secondary Schools

open access: yesEducazione Linguistica Language Education, 2020
The present paper aims to explore how students of Italian secondary schools approach linguistic tasks and what sort of knowledge about language emerges from their analyses. These questions arise from the observation of the results of the Invalsi tests.
Toth, Zuzana
doaj   +1 more source

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns   +10 more
wiley   +1 more source

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