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Multi-objective genetic algorithm for pseudoknotted RNA sequence design
RNA inverse folding is a computational technology for designing RNA sequences which fold into a user-specified secondary structure. Although pseudoknots are functionally important motifs in RNA structures, less reports concerning the inverse folding of ...
Akito eTaneda
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Multiple structural alignment for distantly related all b structures using TOPS pattern discovery and simulated annealing [PDF]
Topsalign is a method that will structurally align diverse protein structures, for example, structural alignment of protein superfolds. All proteins within a superfold share the same fold but often have very low sequence identity and different biological
Gilbert, D, Westhead, DR, Williams, A
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Secondary-Structure Design of Proteins by a Backbone Torsion Energy [PDF]
We propose a new backbone-torsion-energy term in the force field for protein systems. This torsion-energy term is represented by a double Fourier series in two variables, the backbone dihedral angles phi and psi.
Berendsen H. J. C. +30 more
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SumSec: Accurate Prediction of Sumoylation Sites Using Predicted Secondary Structure
Post Translational Modification (PTM) is defined as the modification of amino acids along the protein sequences after the translation process. These modifications significantly impact on the functioning of proteins.
Abdollah Dehzangi +4 more
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Analyzing Secondary Structure Patterns in DNA Aptamers Identified via CompELS
In contrast to sophisticated high-throughput sequencing tools for genomic DNA, analytical tools for comparing secondary structure features between multiple single-stranded DNA sequences are less developed.
Richard Sullivan +3 more
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The α-helix of myosin decreased and the diameter of the myosin clusters increased monotonically with increasing heating time at 50 and 90°C. The clusters that formed during heating at 90°C were much larger than those that formed at 50°C.
Li Yuan +4 more
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Recombinant Goose Circoviruses Circulating in Domesticated and Wild Geese in Poland
Circoviruses are circular single-stranded DNA (ssDNA) viruses that infect a variety of animals, both domestic and wild. Circovirus infection in birds is associated with immunosuppression and this in turn predisposes the infected animals to secondary ...
Tomasz Stenzel +6 more
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Parkinson’s disease is an age-related neurological disorder, and the pathology of the disease is linked to different types of aggregates of α-synuclein or alpha-synuclein (aS), which is an intrinsically disordered protein. The C-terminal domain (residues
Esha Pandit +9 more
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Streamwise vortex structure in plane mixing layers [PDF]
The development of three-dimensional motions in a plane mixing layer was investigated experimentally. It is shown that superimposed on the primary, spanwise vortex structure there is a secondary, steamwise vortex structure.
Bernal, L. P., Roshko, A.
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Jackfruit leaf protein concentrate (LPC) was hydrolyzed by pepsin (H–Pep) and pancreatin (H–Pan) at different hydrolysis times (30–240 min). The effect of the enzyme type and hydrolysis time of the LPC on the amino acid composition, structure, and ...
Carolina Calderón-Chiu +4 more
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