Results 21 to 30 of about 18,178,221 (305)
Noncanonical secondary structures arising from non-B DNA motifs are determinants of mutagenesis
bioRxiv, 2017 Somatic mutations show variation in density across cancer genomes. Previous studies have shown that chromatin organization and replication time domains are correlated with and thus predictive of this variation 1,2,3,4,5.
I. Georgakopoulos-Soares +4 more
semanticscholar +1 more source
The primary, secondary, and structures of higher levels of pectin polysaccharides.
Comprehensive Reviews in Food Science and Food Safety, 2020 Pectin is a heteropolysaccharide abundant in the cell wall of plants and is obtained mainly from fruit (citrus and apple), thus its properties are particularly prone to changes occurring during ripening process.
A. Zdunek, P. Pieczywek, J. Cybulska
semanticscholar +1 more source
Kinetic Target‐Guided Synthesis of Small‐Molecule G‐Quadruplex Stabilizers
ChemistryOpen, 2020 The formation of a G‐quadruplex motif in the promoter region of the c‐MYC protooncogene prevents its expression. Accordingly, G‐quadruplex stabilization by a suitable ligand may be a viable approach for anticancer therapy.
Alice Pomeislová +8 more
doaj +1 more source
Prediction of 8-state protein secondary structures by a novel deep learning architecture
BMC Bioinformatics, 2018 Protein secondary structure can be regarded as an information bridge that links the primary sequence and tertiary structure. Accurate 8-state secondary structure prediction can significantly give more precise and high resolution on structure-based ...
Buzhong Zhang, Jinyan Li, Q. Lv
semanticscholar +1 more source
Protein Science, 2021 Circular dichroism (CD) spectroscopy is a widely‐used method for characterizing the secondary structures of proteins. The well‐established and highly used analysis website, DichroWeb (located at: http://dichroweb.cryst.bbk.ac.uk/html/home.shtml) enables ...
A. Miles, S. G. Ramalli, B. Wallace
semanticscholar +1 more source
Frontiers in Plant Science, 2019 Ligustici Rhizoma et Radix (LReR), an important Chinese medicine known as “Gao-ben,” refers to Ligusticum sinense Oliv. or Ligusticum jeholense Nakai et Kitag.
Zhen-wen Liu, Yu-zhen Gao, Jing Zhou
doaj +1 more source
A balanced secondary structure predictor [PDF]
Journal of Theoretical Biology, 2016 Secondary structure (SS) refers to the local spatial organization of a polypeptide backbone atoms of a protein. Accurate prediction of SS can provide crucial features to form the next higher level of 3D structure of a protein accurately. SS has three different major components, helix (H), beta (E) and coil (C).
Md, Nasrul Islam +3 more
openaire +2 more sources
DNA secondary structures: stability and function of G-quadruplex structures
Nature reviews genetics, 2012 In addition to the canonical double helix, DNA can fold into various other inter- and intramolecular secondary structures. Although many such structures were long thought to be in vitro artefacts, bioinformatics demonstrates that DNA sequences capable of
Matthew L. Bochman +2 more
semanticscholar +1 more source
Modelling DNA and RNA secondary structures using matrix insertion–deletion systems
International Journal of Applied Mathematics and Computer Science, 2016 Insertion and deletion are operations that occur commonly in DNA processing and RNA editing. Since biological macromolecules can be viewed as symbols, gene sequences can be represented as strings and structures can be interpreted as languages.
Kuppusamy Lakshmanan, Mahendran Anand
doaj +1 more source
RNA: A publication of the RNA Society, 2016 RNA secondary structure prediction is widely used to analyze RNA sequences. In an RNA partition function calculation, free energy nearest neighbor parameters are used in a dynamic programming algorithm to estimate statistical properties of the secondary ...
Michael F. Sloma, D. Mathews
semanticscholar +1 more source