Results 101 to 110 of about 560,014 (299)

Cytokine‐Engineered Chimeric Antigen Receptor‐T Cell Therapy: How to Balance the Efficacy and Toxicity

Advanced Science, EarlyView.
Cytokine‐engineered CAR‐T cells represent a promising immunotherapy against malignancies due to direct tumor killing and potent immunity response. However, significant toxicities, including CRS and ICANS, have restricted clinical applications. How to keep the risk‐benefit balance of the advanced therapy is of great importance for maximizing the benefit
Xinru Zhang, Gulizeba Aimaiti, Yuanye Guan, Yuzhe Sha, Wei Zhou, Jiefeng Shen, Bo Zhao, Wei‐En Yuan   +7 more
wiley   +1 more source

Nanozymes Integrated Biochips Toward Smart Detection System

Advanced Science, EarlyView.
This review systematically outlines the integration of nanozymes, biochips, and artificial intelligence (AI) for intelligent biosensing. It details how their convergence enhances signal amplification, enables portable detection, and improves data interpretation.
Dongyu Chen, Wang Zheng, Zhihui Zhang, Shenping Yu, Xinxin Hang, Han Wu, Xiao‐Wei Xiang, Wei Mu, Yanli Jiao, Zaizai Dong, Lingqian Chang   +10 more
wiley   +1 more source

UAV Swarm-Enabled Aerial CoMP: A Physical Layer Security Perspective

IEEE Access, 2019
Unlike aerial base station enabled by a single unmanned aerial vehicle (UAV), aerial coordinated multiple points (CoMP) can be enabled by a UAV swarm. In this case, the management of multiple UAVs is important.
Xuanxuan Wang, Wei Feng, Yunfei Chen, Ning Ge   +3 more
doaj   +1 more source

Polarization‐Dependent 3D Holography Generated by Inverse Design Nanoprinting Metasurface

Advanced Science, EarlyView.
A novel polarization‐dependent 3D holography is proposed by introducing polarization as an additional freedom, enabling enhanced depth selectivity and greater control over holographic reconstruction. The efforts perfectly combine the polarization and 3D holography display into ADAM gradient descent algorithm, the application of nanoprinting further ...
Lingxing Xiong, Jintao Gong, Fei Zhang, Wenhao Miao, Qiong He, Dapeng Zhang, Yangjian Cai, Nan Chi   +7 more
wiley   +1 more source

Physical Layer Security in Cognitive Millimeter Wave Networks

IEEE Access, 2019
Millimeter wave (mmWave) communications and cognitive radio networks are two key technologies to improve the spectral efficiency. For a cognitive mmWave wiretap network in which randomly located eavesdroppers may reside in the signal beam of the ...
Yi Song, Weiwei Yang, Xiaoqin Yang, Zhongwu Xiang, Biao Wang   +4 more
doaj   +1 more source

Trojan Horse Strategy: How Biomimetic Nanomedicine Remodels the Tumor Microenvironment

Advanced Science, EarlyView.
This review focuses on biomimetic nanomedicines for tumor microenvironment (TME) remodeling, covering their diverse biomimetic types, design principles, and mechanisms of immune cell reprogramming and reversal of immunosuppressive microenvironments, with particular emphasis on their application in synergistic immunotherapy.
Wanrong Wang, Siqi Mu, Juan Zhang, Guisong Shan, Xueqian Li, Ran Wang, Tao Guo, Xiaoyan He   +7 more
wiley   +1 more source

Physical Layer Security in Cognitive Untrusted Relay Networks

IEEE Access, 2018
In this paper, we consider the secure communications in a cognitive untrusted relay network, where the secondary source intends to communicate with a secondary destination through an untrusted relay in the presence of the direct source-destination link ...
Dechuan Chen, Yunpeng Cheng, Weiwei Yang, Jianwei Hu, Yueming Cai   +4 more
doaj   +1 more source

ADAMTS9‐AS2 Disrupts Docetaxel‐Resistance in Castration‐Resistant Prostate Cancer via Stemness Suppression and Ferroptosis Induction

Advanced Science, EarlyView.
This study uncovered a dual‐track mechanism by which ADAMTS9‐AS2 overcame chemoresistance in CRPC: suppressing cancer stemness through the FOXF2/TGF‐β2 pathway, and triggering ferroptosis via competitive SLC7A11 sequestration. Polymeric materials co‐targeting these vulnerabilities further boost docetaxel sensitivity, highlighting a compelling strategy ...
Ji Liu, Yan Gao, Yadong Guo, Junfeng Zhang, Wentao Zhang, Zhuoran Gu, Haotian Chen, Chengqi Jin, Peng Luo, Shiyu Mao, Yajuan Hao, Shuo Shi, Xudong Yao   +12 more
wiley   +1 more source

On the Performance of Random Cognitive mmWave Sensor Networks

Sensors, 2019
This paper investigates the secrecy performance of a cognitive millimeter wave (mmWave) wiretap sensor network, where the secondary transmitter (SU-Tx) intends to communicate with a secondary sensor node under the interference temperature constraint of ...
Yi Song, Weiwei Yang, Zhongwu Xiang, Biao Wang, Yueming Cai   +4 more
doaj   +1 more source

Mapping CSC‐Mediated Ovarian Cancer Chemoresistance via CXCR4‐PET to Guide Precision Cisplatin Re‐Sensitization Therapy

Advanced Science, EarlyView.
CXCR4 functions as a potential cancer stem cell‐associated marker linked to chemoresistance in ovarian cancer, and an inhibitor of CXCR4, AMD3100, can enhance the cytotoxic response to cisplatin. Based on these findings, [68Ga]Ga‐Pentixafor positron emission tomography enables selective visualization of CXCR4‐high ovarian cancer, while AMD3100 combined
Lixia Feng, Simei Zhao, Zheng Wei, Wenwen Wang, Feiquan Ying, Lin Huang, Mengna Zhu, Mengqing Chen, Qiang Yang, Si Sun, Dawei Jiang, Lingling Gao, Jing Cai   +12 more
wiley   +1 more source