This study presents a custom‐made soft pneumatic device (SPD) that mimics complex mechanical forces and fluid flow to enhance in vitro cell differentiation. It shows that low mechanotransduction promotes MSC differentiation into osteoprogenitor cells, while high mechanotransduction causes structural disruptions and cell detachment, providing new ...
Gwang‐Bum Im+9 more
wiley +1 more source
Effects of photoperiod change on serum hormone level, hair follicle growth and antioxidant status in skin tissue of cashmere goats. [PDF]
Mao C, Yin X, Wang C, Huang X, Li J.
europepmc +1 more source
This study presents a novel implantable drug delivery systemwith a biodegradable poly(caprolactone) membrane and compressed drug core forsustained release. These implantable devices deliver risperidone in vitro for 170 days and in vivo for 49 days in rats, showing promise for chronic conditions like schizophrenia.
Linlin Li+9 more
wiley +1 more source
Critical illness and sex hormones: response and impact of the hypothalamic-pituitary-gonadal axis. [PDF]
Ma Y+6 more
europepmc +1 more source
This study developed a biomimetic scaffold incorporating PDRN and melatonin to restore ovarian function in chemotherapy‐induced premature ovarian insufficiency, enhancing cell survival, folliculogenesis, and hormone normalization, while improving fertility rates and offspring in a mouse model, offering a promising strategy for ovarian function ...
Da‐Seul Kim+8 more
wiley +1 more source
Acidosis regulates immune progression in rheumatoid arthritis by promoting the expression of cytokines and co-stimulatory molecules in synovial fibroblasts. [PDF]
Qian X+9 more
europepmc +1 more source
Engineering the Future of Restorative Clinical Peripheral Nerve Surgery
What if damaged nerves could regenerate more effectively? This review unveils cutting‐edge strategies to restore nerve function, from biomaterial scaffolds and bioactive molecules to living engineered tissues. By accelerating axonal regrowth, preserving Schwann cells, and enhancing connectivity, these approaches are reshaping nerve repair—offering new ...
Justin C. Burrell+5 more
wiley +1 more source
Establishing the Role of Liver Fatty Acid-Binding Protein in Post-Golgi Very-Low-Density Lipoprotein Trafficking Using a Novel Fluorescence-Based Assay. [PDF]
Winterfeldt K, Tasin FR, Siddiqi SA.
europepmc +1 more source
The scaffold‐free Anchored Cell Sheet Engineering platform is used to create three‐dimensional (3D) in vitro models of skeletal muscle tissue that replicate key features of Duchenne and Myotonic dystrophies. These personalized tissue models, validated by histological, immunostaining, and proteomics analyses, accurately mimic disease phenotypes and ...
Alireza Shahin‐Shamsabadi+1 more
wiley +1 more source
BuZhong YiQi Formula Alleviates Diabetes-Caused Hyposalivation by Activating Salivary Secretion Pathway in the Parotid and Submandibular Glands of Rats. [PDF]
Wang MY+8 more
europepmc +1 more source