Association of Salivary ABO Antigen Expression and Dental Caries Experience
Dentistry 3000This study aimed to determine ABO blood group phenotypes and secretor status from saliva samples and to evaluate their association with dental caries experience among Iraqi primary schoolchildren. A cross-sectional study was conducted among 88 children
Zainab Kadhim Mohamed Jawad +2 more
doaj +1 more source
Reprogramming tumor cells with LCOR mRNA nanotherapy to enhance immunotherapy
Molecular Oncology, EarlyView.LCOR (Ligand‐dependent corepressor) mRNA encapsulated in polymeric nanoparticles restores LCOR activity in tumor cells, constraining aggressive tumor cell states and increasing tumor immunogenicity. This reprogramming makes tumor cells more vulnerable to T‐cell attack and enhances their response to immune‐checkpoint immunotherapy.
Gabriel Serra‐Mir +9 more
wiley +1 more source
Molecular Oncology, EarlyView.This paper shows that size‐exclusion chromatography and sequential centrifugation applied to seminal plasma enrich for different populations of extracellular vesicles. This may significantly affect the detection and analysis of extracellular vesicle‐associated cancer biomarkers.
Elen Telumyan +8 more
wiley +1 more source
Engineering IL‐4 resistant proinflammatory human myeloid cells for cancer immunotherapy
Molecular Oncology, EarlyView.We developed a scalable workflow to generate proinflammatory human myeloid cells. CRISPR/Cas9‐edited CD34+ hematopoietic stem and progenitor cells were expanded and differentiated with M‐CSF. Deletion of STAT6 or STAT6/NFKB1 enhanced macrophage proinflammatory gene expression and cytokine secretion in the presence of IL‐4 while maintaining antibody ...
Theresa Barberi, Alan D. Friedman
wiley +1 more source
Spatial heterogeneity of hotspot mutations and clonal relatedness in ovarian endometrioid carcinoma
Molecular Oncology, EarlyView.Spatially resolved analysis revealed heterogeneous distributions of selected cancer‐associated mutations within ovarian endometrioid carcinomas. Shared mutations between paired endometrial and ovarian tumors supported clonal relatedness. These findings highlight the value of sampling multiple tumor regions when interpreting molecular profiles ...
Takahito Ashihara +10 more
wiley +1 more source
Tumour‐proximal deep serum proteomics identifies biomarkers associated with ovarian cancer
Molecular Oncology, EarlyView.New biomarkers are needed for early ovarian cancer detection. Ovarian (tumour‐proximal) and peripheral vein serum from healthy women and patients with benign or malignant tumours underwent nanoparticle‐enriched deep proteomics. Ovarian serum yielded more protein identifications and revealed tumour‐reflective signatures.
Darren Lau +9 more
wiley +1 more source
Blood Grouping Made Painless: Detecting ABO from Human Saliva.
Malaysia Journal of Invention and InnovationThe frequency of ABH secretor status was studied by detecting the ABH blood group substance using the standard tube-hemagglutination inhibition technique in the saliva of 30 students from Varee Chiangmai School, grades 10 to 12.
Karnchanok Srigrid +2 more
doaj
Quantitative Profiling of Human Milk Oligosaccharides Across Asian Countries Reveals Secretor-Dependent Variations and Implications for Infant Nutrition. [PDF]
Int J Mol SciNguyen MTT +13 more
europepmc +1 more source
Human Milk Bioactive Compounds and Psychomotor Outcomes in Infants and Children: A Systematic Review. [PDF]
Mol Nutr Food ResHuber L +3 more
europepmc +1 more source
Bile and capsid variation coregulate histo-blood group antigen recognition and serum neutralization potency in GII.12 human norovirus. [PDF]
J VirolMallory ML +11 more
europepmc +1 more source