Results 101 to 110 of about 242,930 (301)

Mucosa-Environment Interactions in the Pathogenesis of Rheumatoid Arthritis [PDF]

, 2019
Mucosal surfaces play a central role in the pathogenesis of rheumatoid arthritis (RA). Several risk factors, such as cigarette smoking, environmental pollution, and periodontitis interact with the host at the mucosal level, triggering immune system ...
Conti, Fabrizio, Di Franco, Manuela, Guzzo, Maria Paola, Iannuccelli, Cristina, Lucchino, Bruno, Spinelli, Francesca Romani   +5 more
core   +1 more source

Circulating anti-citrullinated protein antibodies containing secretory component are prognostic for arthritis onset in at-risk patients. [PDF]

Clin Exp Immunol, 2021
Roos Ljungberg K, Martinsson K, Wetterö J, Svärd A, Kastbom A.   +4 more
europepmc   +1 more source

The Effects of Pregnenolone 16α-Carbonitrile Dosing on Digoxin Pharmacokinetics and Intestinal Absorption in the Rat [PDF]

, 2010
The effect of Pgp induction in rats by pregnenolone 16α-carbonitrile (PCN) (3 days, 35 mg/kg/d, p.o.) on digoxin pharmacokinetics and intestinal transport has been assessed.
Anna-Lena Ungell, Bauer, Britt-Marie Fihn, Constanze Hilgendorf, Englund, Harrison, Iain S. Haslam, Johan E. Karlsson, Lam, Nicholas L. Simmons, Noe, Read, Simon Lowes   +12 more
core   +2 more sources

Respiratory Organ‐on‐a‐Chip for Disease Modeling: From Architecture to Functional Integration

Advanced Healthcare Materials, EarlyView.
Respiratory organ‐on‐a‐chip (ROC) models capture key mechanical and cellular cues of the human respiratory system, enabling quantitative dissection of disease mechanisms. This review links ROC architectures to disease modeling, functional integration, and commercialization, and proposes a decision framework that aligns model complexity with mechanistic
Jinzhuo Hu, Yongjie Tang, Sidi Liu, Tao Xu, Qian Liu   +4 more
wiley   +1 more source

Bio-molecular characterization of stress enzyme profile on esterase in selected silkworm races of Bombyx mori (L.) for biomarker selection

Advances in Biomarker Sciences and Technology, 2019
Silkworm Bombyx mori exhibits for eliminating pathogenic defenses by their secretory component of haemolymph and gut component. This study aimed to investigate the stress enzyme role of carboxyl esterase, plays a major function in toxic component ...
S. Vishnu Priya, P. Somasundaram
doaj   +1 more source

A Superhydrophobic 3D Cell Culture System Reveals the Mechanobiological Role of Cancer‐Associated Fibroblasts in Prostate Cancer Metastasis

Advanced Healthcare Materials, EarlyView.
A superhydrophobic 3D cell culture platform enables rapid and consistent formation of heterotypic tumor–stroma clusters, and reveals how physiological shear conditions influence metastatic signaling. Mechanical stimulation of cancer‐associated fibroblasts promotes sustained cytokine secretion and survival‐promoting pathways, showing how multicellular ...
Alexandria T. Carter, Abigail R. Fabiano, Ehsan Aalaei, Jason Deng, Dakota E. Rostant, Michael R. King   +5 more
wiley   +1 more source

Localization of Na pumps in the tracheal epithelium of the dog. [PDF]

, 1979
Binding of [3H]ouabain by the dog's tracheal epithelium shows a nonspecific component depending linearly on ouabain concentration, and a specific saturable component with a Km of 10(-7) M.
Basbaum, CB, Widdicombe, JH, Yee, JY
core  

Epidermal Patch Technologies for Integrated Healthcare and Infection Management

Advanced Healthcare Materials, EarlyView.
Epidermal patches have evolved from simple wound coverings into multifunctional, skin‐conformable platforms integrating drug delivery, biosensing, and therapeutic functionalities. This review highlights their material innovations, fabrication strategies, and intelligent designs, including hydrogels, microneedles, and flexible electronics, while ...
Yuqi Wang, Atakan Tevlek, Pawel L. Urban, Boaz Mizrahi, Onome Ejeromedoghene, Roshan Deen, Yuanjing Lin, Jagan Mohan Dodda   +7 more
wiley   +1 more source

RAT SERUM IMPROVES RAT PSEUDOISLET FORMATION AND INSULIN GENE EXPRESSION

Journal of Biological Research
Langerhana islets are constituted by four different cellular populations with a central core of  cells surrounded by ,  and PP cells. Islets may be dissociated to single component cells that re-establish contacts to form organized and functional ...
L. Lione, A. Puddu, A. Pedemonte, G.L. Viviani   +3 more
doaj   +1 more source

Secretory carcinoma of the breast, commonly exhibits the features of low grade, triple negative breast carcinoma- A Case report with updated review of literature

Autopsy and Case Reports, 2021
Secretory carcinoma of the breast (SBC) is a rare breast neoplasm. Most of the patients present at an early stage with a relatively indolent clinical course. Lymph node and distant metastasis are also very infrequent.
Nirmalya Banerjee, Devmalya Banerjee, Neha Choudhary   +2 more
doaj