Results 41 to 50 of about 122,105 (257)
Molecular Oncology, EarlyView.Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim +3 more
wiley +1 more source
CEACAM1 participation in breast cancer progression
Molecular Oncology, EarlyView.In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin +3 more
wiley +1 more source
Planta Daninha, 2006 Porophyllum ruderale (Asteraceae) é uma erva ruderal e aromática conhecida popularmente como couve-cravinho. Na medicina popular, é utilizada como cicatrizante e antiinflamatória, antifúngica, antibacteriana, calmante, no combate à hipertensão arterial ...
M.C.M. Fonseca +2 more
doaj +1 more source
Structure Formation in the Cell's Secretory Pathway [PDF]
Biophysical Journal, 2011 Virtually all membrane proteins, i.e. about 30% of the cell's proteom, enter the endoplasmic reticulum (ER) during or after translation. Having cleared the ER quality control, these proteins are packaged into small transport vesicles at so-called ‘ER exit sites’. Vesicles emerging at ER exit sites shuttle their protein cargo to the cell's major hub for
openaire +1 more source
YIPFα1A expression is regulated by multilayered molecular mechanisms
FEBS Open Bio, EarlyView.YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji +2 more
wiley +1 more source
Acta Botânica BrasílicaMimosa baptistae is a new species presenting stalked glandular trichomes that give it a glutinous appearance, mainly with respect to the leaflets. Furthermore, it is an aculeate species, with multijugate leaves, white stamens, and fruits also covered by ...
Fernanda Schmidt Silveira +3 more
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FEBS Open Bio, EarlyView.The brown marmorated stink bug, Halyomorpha halys, mainly secretes 4‐oxo‐(E)‐2‐hexenal, (E)‐2‐decenal, dodecane and tridecane, a mixture representative of that released by many heteropterans. We demonstrated that H. halys can synthesise these secretory components de novo using dietary glucose.
Haruna Fujimori, Koji Noge
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The anatomical and histochemical properties of endemic species Leiotulus aureus (Apiaceae) [PDF]
Comprehensive Plant BiologyLeiotulus aureus is an endemic umbellifer of the Balkan Peninsula and Turkey. It belongs to the rather complex tribe Tordylieae, whose genera are carpologically characterised in detail.
Miljan Bigović +4 more
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Secretory Structures of Pogostemon auricularius: Morphology, Development, and Histochemistry [PDF]
Symmetry, 2018 Pogostemon auricularius, an aromatic plant in Lamiaceae, has wide application in pharmaceutical preparations. However, little is known about the secretory structures that contain the medicinal compounds. In this study, two kinds of glandular trichome types, including peltate glandular trichomes and short-stalked capitate trichomes, were identified in ...
Jiansheng Guo, Cheng Zhou
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FEBS Open Bio, EarlyView.Glioblastoma cells express calcitonin receptor variants (CT receptor isoforms) that may help them survive stress. Using qPCR, transcript‐specific long‐read nanopore sequencing, immunofluorescence co‐localisation and comparative sequence analysis, this study identifies a novel alternatively spliced CALCR transcript that encodes the CTb receptor isoform ...
Pragya Gupta +7 more
wiley +1 more source