Results 51 to 60 of about 122,105 (257)

Leaf anatomy of Xylopia L. (Annonaceae), occurring in Ecological Park of Gunma, Santa Bárbara, Pará State [PDF]

open access: yesBoletim do Museu Paraense Emílio Goeldi. Ciências Naturais, 2009
Annonaceae shows several species which are producers of essential oil, among them Xylopia genus, that shows medicinal, pharmacological and biological properties.
Eliane Francisca de Almeida   +3 more
doaj  

Comparative leaf morphology and anatomy of three Asteraceae species

open access: yesBrazilian Archives of Biology and Technology, 2006
The objective of this paper was to describe and compare the morphology and anatomy of mature leaves of Mikania glomerata Spreng., Porophyllum ruderale Cass.
Patricia Milan   +2 more
doaj   +1 more source

Structure and Catalytic Mechanism of Secretory Phospholipases A2

open access: yes, 1994
Publisher Summary This chapter focuses on the aspects of phospholipases A 2 (sPLA 2 ) structure that are of particular relevance to catalysis. A formal reaction pathway based largely on high-resolution structure analysis of crystalline complexes of secretory phospholipids (sPLA 2 s) with a transition-state analog is proposed.
D L, Scott, P B, Sigler
openaire   +2 more sources

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

open access: yesAging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

Unraveling 4‐Phenylbutyrate's Therapeutic Role in SLC6A1 Disorders: Pharmacochaperoning Over HDAC Inhibition

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Variants in SLC6A1, encoding the GABA transporter 1 (GAT‐1), cause epilepsy, autism spectrum disorder, and developmental delay via loss of GABA uptake, impaired trafficking, and ER retention. We previously found that 4‐Phenylbutyrate (PBA), an FDA‐approved drug, restores GABA uptake and reduces seizures in SLC6A1‐related disorders ...
Melissa B. DeLeeuw   +5 more
wiley   +1 more source

Nanofiber‐Supported Decellularized Matrix Membrane Creates a Biomimetic Biochemical and Biophysical Niche for Intestinal Organoid Epithelium

open access: yesAdvanced Healthcare Materials, EarlyView.
A nanofiber‐supported decellularized extracellular matrix (NaDE) membrane recreates key biochemical and mechanical features of native intestinal tissue. This platform enables the formation of a more physiologically relevant intestinal epithelium, enhancing stem cell maintenance and promoting diverse cell differentiation.
Jaeseung Youn   +7 more
wiley   +1 more source

Morphoanatomy of nectaries of Chamaecrista (L.) Moench sections Chamaecrista , Caliciopsis and Xerocalyx (Leguminosae: Caesalpinioideae)

open access: yesActa Botânica Brasílica
Nectaries are specialized structures that secrete nectar. Several species of Chamaecrista possess nectaries on the petiole, which have been shown to vary widely in morphology and the chemical nature of their secretion.
Marinalva dos Santos Silva   +3 more
doaj   +1 more source

A 3D Human Neuron‐on‐Chip Platform to Monitor Neuronal Injury Responses

open access: yesAdvanced Healthcare Materials, EarlyView.
This study presents a novel 3D Neuron‐on‐Chip model that can maintain human PSC‐derived excitatory prefrontal cortex neurons in 3D hydrogels and can be used to monitor neuronal injury responses over time. Results show injury‐induced acute neuronal excitotoxicity, declining neuronal connectivity, and the activation of a neurodegenerative, SASP‐like ...
Ruiping Tang   +16 more
wiley   +1 more source

Pericarp ontogeny of Tapirira guianensis Aubl. (Anacardiaceae) reveals a secretory endocarp in young stage

open access: yesActa Botânica Brasílica
Most species of Anacardiaceae have drupes containing secretory structures.. The substances produced by these structures may have importance to industry and folk medicine, and may even cause allergenic effects. This work describes the ontogeny of pericarp
Elisabeth Emilia Augusta Dantas Tölke   +3 more
doaj   +1 more source

Microfluidic Nano‐Assembly of Red‐Blood‐Cell (RBC) Lipids and Components for Engineering Extracellular Vesicles

open access: yesAdvanced Healthcare Materials, EarlyView.
Engineered red blood cell‐derived extracellular vesicles (eRBCEVs) are synthesized via controlled microfluidic assembly from native RBC lipids, enabling tunable encapsulation of proteins, nucleic acids, nanoparticles, and viral vectors. The platform demonstrates reproducible nanoscale architecture, preserved membrane composition, and functional cargo ...
Chiranth K. Nagaraj   +23 more
wiley   +1 more source

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