Results 41 to 50 of about 18,140 (258)

Comparative Evaluation of Hemodiafiltration, Hemoperfusion, and Standard Hemodialysis on Efficacy, Inflammatory Control, Dialysis Adequacy, and Safety in End‐Stage Renal Disease: A Prospective Observational Study

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Chronic micro‐inflammation in patients with end‐stage renal disease (ESRD) is a significant driver of cardiovascular complications and diminished quality of life. While standard hemodialysis (SHD) effectively manages small‐molecule clearance, its ability to remove medium‐to‐large uremic toxins—the primary catalysts of systemic ...
Hongwei Zuo   +5 more
wiley   +1 more source

Evaluation of the nutritional status of rural children living in Zambia

open access: yesJournal of Physiological Anthropology, 2020
Background Growth references (growth charts) are used to assess the nutritional and growth status of children. In developed countries, there are growth charts based on the country’s national surveys.
Arimi Mitsunaga, Taro Yamauchi
doaj   +1 more source

Linear and ponderal growth changes in boys and girls from Puerto Madryn (Patagonia, Argentina) between 2001 and 2016

open access: yesHuman Biology and Public Health, 2022
Background: The phenotypic plasticity in growth pattern that takes place over time is described as “secular trend”. The presence of secular changes evidences shifts in the environmental conditions under which a population lives.
Bárbara Navazo   +1 more
doaj   +1 more source

Mixed‐class J‐domain protein scaffolds promote expanded aggregate handling and multivalent Hsp70 engagement during functional disaggregase assembly

open access: yesFEBS Letters, EarlyView.
Protein aggregates threaten proteostasis and cell health. In human cells, Hsp70–J‐domain protein‐based disaggregases remove aggregates, but how they assemble remains unclear. Our biochemical findings show that DNAJA2‐ and DNAJB1‐containing disaggregase scaffolds enhance luciferase aggregate targeting, and that Hsp70 recruitment by both J‐domain ...
Anna Szlachcic, Nadinath B. Nillegoda
wiley   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

The changes in the prevalence of underweight and short stature among Polish youth from 1938 to 2020

open access: yesAnnals of Human Biology
Background The issues of underweight and short stature are significant yet underrepresented in the literature.Aim This study examines the prevalence of changes in underweight and short stature among Polish youth from 1938 to 2020.Subjects and methods ...
Łukasz Kryst   +3 more
doaj   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner   +14 more
wiley   +1 more source

[Secular trends in breastfeeding in Brazil].

open access: yesRevista de saude publica, 2013
The objective of this study was to document the secular trend in breastfeeding in Brazil. Data bases from seven national surveys conducted from 1975 to 2008 were reanalyzed. To obtain compatible data from the different surveys, children in the same age group and the same indicators were analyzed, using the same statistical techniques.
Venancio, Sonia Isoyama   +2 more
openaire   +2 more sources

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

open access: yesMolecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen   +14 more
wiley   +1 more source

Changes in the Morphological Development of Youth aged 16-18 from Eastern Poland in the Years 2006 - 2016 – 2021

open access: yesCentral European Journal of Sport Sciences and Medicine
On the one hand, the number of individuals with excess body weight is increasing, while on the other, the issue of malnutrition among adolescents is becoming increasingly noticeable.
Agnieszka Wasiluk, Jerzy Saczuk
doaj   +1 more source

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