Results 51 to 60 of about 18,140 (258)

The correlation between solar and geomagnetic activity – Part 2: Long-term trends [PDF]

Annales Geophysicae, 2011
Using lag-correlation function analysis, the correlation coefficient at zero lag (r0), the maximum (rm) and the corresponding lag time (Lm) between solar (Rz) and geomagnetic (aa) activity for a 528-month (44-year) running time window are shown to ...
Z. L. Du
doaj   +1 more source

Longitudinal genome‐wide aneuploidy measurements in circulating cell‐free DNA to predict lack of benefit from pembrolizumab in patients with metastatic urothelial cancer

Molecular Oncology, EarlyView.
Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi, Stavros Makrodimitris, Sandra van Wilpe, Iris te Paske, Vanja de Weerd, Corine M. Beaufort, Hans M. Westgeest, Jens Voortman, Maureen J. B. Aarts, Maud Rijnders, Astrid A. M. van der Veldt, Ronald de Wit, Niven Mehra, Saskia M. Wilting, Debbie G. J. Robbrecht   +14 more
wiley   +1 more source

THE SECULAR TREND OF PHYSICAL DEVELOPMENT IN MODERN MEDICAL PRACTICE

Мать и дитя в Кузбассе, 2021
The physical development of a child is continuously being influenced by many environmental factors: physical, psychological, social and economic ones. Nowadays, children experience high intellectual loads in secondary as well as in preschool educational ...
Нина Константиновна Перевощикова, Илья Александрович Селиверстов, Светлана Альбертовна Дракина, Наталья Степановна Черных   +3 more
doaj  

Underweight, overweight, and obesity in boys and girls at the age of 7–18 years from eastern Poland in the years 1986–2006

Studia Medyczne, 2015
Introduction : Increasing disproportions in the economic status of the Polish population are tangibly reflected in differences in the nutritional status of children and adolescents.
Agnieszka Wasiluk, Jerzy Szczuk
doaj   +1 more source

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

Molecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski, Júlia Perera‐Bel, Alejo Rodriguez‐Vida, Nuria Juanpere, Jihyun Lee, Daniel E. Michaud, Jennifer L. Guerriero, Kent W. Mouw, Aristotelis Bamias, Filipe L. F. Carvalho, Joaquim Bellmunt   +10 more
wiley   +1 more source

Secular trends of birthweight in boys from 1950 to 2010

Pediatrics and Neonatology, 2019
Background: Birthweight is an indicator of fetal development and intrauterine conditions and is associated with future health outcomes. Secular birthweight trends prior to the 1970s are mostly unknown. Our aim was to explore secular birthweight trends in
Jimmy Célind, Marie Hedlund, Maria Bygdell, Arvid Sondén, Anders Elfvin, Jenny M. Kindblom   +5 more
doaj   +1 more source

Patient therapy outcome modeling in cancer organoids is improved by cancer‐associated fibroblasts and organoid assembly convolution

Molecular Oncology, EarlyView.
Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski, Liudmyla Dolinchuk, Michał Jerzak, Albert Gandurski, Tomasz Grochowski, Weronika Wojtyś, Maciej Zadrożny, Wojciech Kaźmierczak, Małgorzata Lenarcik, Marta Matejak‐Górska, Radosław Samsel, Tomasz Olesiński, Dawid Walerych   +12 more
wiley   +1 more source

The skills required for transition to university and study in biological sciences: A student perspective

FEBS Open Bio, EarlyView.
Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley   +1 more source

Secular trends in physical growth, biological maturation, and intelligence in children and adolescents born between 1978 and 1993

Frontiers in Public Health
IntroductionHuman physical growth, biological maturation, and intelligence have been documented as increasing for over 100 years. Comparing the timing of secular trends in these characteristics could provide insight into what underlies them.
Dominique A. Eichelberger, Aziz Chaouch, Valentin Rousson, Tanja H. Kakebeeke, Tanja H. Kakebeeke, Jon Caflisch, Jon Caflisch, Flavia M. Wehrle, Flavia M. Wehrle, Flavia M. Wehrle, Oskar G. Jenni, Oskar G. Jenni, Oskar G. Jenni   +12 more
doaj   +1 more source

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

FEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani, Eiman Y. Ibrahim, Rozalyn L. Rodwin, Leah M. Ferrucci, Kim Blenman, Maryam Lustberg, Barbara E. Ehrlich   +6 more
wiley   +1 more source