Results 51 to 60 of about 18,178 (257)

Identifying gene expression signatures for risk stratification of postoperative adjuvant chemotherapy in colorectal cancer

FEBS Open Bio, EarlyView.
A novel signature integrating genome‐wide analysis with clinical factors predicts recurrence in stage II colorectal cancer and enables a new risk stratification to guide postoperative adjuvant chemotherapy. Clinical risk stratification for postoperative recurrence in patients with pathological stage II (pStage II) colorectal cancer (CRC) is essential ...
Mayuko Otomo, Keisuke Okuno, Shuichi Watanabe, Sakiko Oba, Hiroyasu Kagawa, Masanori Tokunaga, Daisuke Ban, Yusuke Kinugasa   +7 more
wiley   +1 more source

Changes in the Morphological Development of Youth aged 16-18 from Eastern Poland in the Years 2006 - 2016 – 2021

Central European Journal of Sport Sciences and Medicine
On the one hand, the number of individuals with excess body weight is increasing, while on the other, the issue of malnutrition among adolescents is becoming increasingly noticeable.
Agnieszka Wasiluk, Jerzy Saczuk
doaj   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

THE SECULAR TREND OF PHYSICAL DEVELOPMENT IN MODERN MEDICAL PRACTICE

Мать и дитя в Кузбассе, 2021
The physical development of a child is continuously being influenced by many environmental factors: physical, psychological, social and economic ones. Nowadays, children experience high intellectual loads in secondary as well as in preschool educational ...
Нина Константиновна Перевощикова, Илья Александрович Селиверстов, Светлана Альбертовна Дракина, Наталья Степановна Черных   +3 more
doaj  

Underweight, overweight, and obesity in boys and girls at the age of 7–18 years from eastern Poland in the years 1986–2006

Studia Medyczne, 2015
Introduction : Increasing disproportions in the economic status of the Polish population are tangibly reflected in differences in the nutritional status of children and adolescents.
Agnieszka Wasiluk, Jerzy Szczuk
doaj   +1 more source

Evaluating the effect of γ‐oryzanol on MASLD pathology using a medaka fish model

FEBS Open Bio, EarlyView.
This study explores a liver disease called MASLD, which is increasing worldwide and can lead to serious damage. Researchers used medaka fish instead of rodents to test a food compound, γ‐oryzanol. Fish fed this compound had less liver fat and healthier gut bacteria.
Yukako Ito, Haduki Asano, Ayano Ueki, Joe Sakamoto, Yasuhiro Kamei, Hayato Tokumoto, Ayaka Yazawa, Shigeki Kamitani   +7 more
wiley   +1 more source

Secular trends in physical growth, biological maturation, and intelligence in children and adolescents born between 1978 and 1993

Frontiers in Public Health
IntroductionHuman physical growth, biological maturation, and intelligence have been documented as increasing for over 100 years. Comparing the timing of secular trends in these characteristics could provide insight into what underlies them.
Dominique A. Eichelberger, Aziz Chaouch, Valentin Rousson, Tanja H. Kakebeeke, Tanja H. Kakebeeke, Jon Caflisch, Jon Caflisch, Flavia M. Wehrle, Flavia M. Wehrle, Flavia M. Wehrle, Oskar G. Jenni, Oskar G. Jenni, Oskar G. Jenni   +12 more
doaj   +1 more source

Secular trends of birthweight in boys from 1950 to 2010

Pediatrics and Neonatology, 2019
Background: Birthweight is an indicator of fetal development and intrauterine conditions and is associated with future health outcomes. Secular birthweight trends prior to the 1970s are mostly unknown. Our aim was to explore secular birthweight trends in
Jimmy Célind, Marie Hedlund, Maria Bygdell, Arvid Sondén, Anders Elfvin, Jenny M. Kindblom   +5 more
doaj   +1 more source

Avidin is evolutionarily conserved in fish but dispensable for development and resistance against Streptococcus agalactiae in zebrafish

FEBS Open Bio, EarlyView.
The presence of biotin‐binding avidin proteins in fish and their biological significance are poorly characterized. We cataloged fish avidins and demonstrate that they are widely present and evolutionarily conserved. We created avd knockout zebrafish and show that zebavidin is dispensable for development and that resistance of avd knockout embryos in ...
Anni K. Saralahti, Markus J. T. Ojanen, Mataleena Parikka, Otto Kauko, Mika Rämet, Vesa P. Hytönen   +5 more
wiley   +1 more source

Risk Prediction Models for Recurrence After Curative Treatment of Early‐Stage or Locally Advanced Lung Cancer: A Systematic Review

Aging and Cancer, EarlyView.
This systematic review synthesizes prognostic models for survival and recurrence in resected non‐small cell lung cancer. While many models demonstrate moderate to good discrimination, few are externally validated and reporting quality is variable, limiting clinical applicability and highlighting the need for robust, transparent model development ...
Evangeline Samuel, S. Tissera, E. Paul, J. Zalcberg, R. G. Stirling   +4 more
wiley   +1 more source