Results 71 to 80 of about 14,851 (262)

DNA ligase LigE increases bacterial transformation with damaged extracellular DNA

open access: yesFEBS Letters, EarlyView.
The DNA ligase LigE from the naturally competent Gram‐negative bacterium Neisseria gonorrhoaea increases transformation with cut extracellular DNA. This process is ATP‐dependent and relies on the catalytic activity of LigE; it also requires that LigE contains an intact periplasmic localisation sequence, indicating that ligE functions in the periplasm ...
Jolyn Pan   +4 more
wiley   +1 more source

Secular variation on the territory of the Czech Republic and reduction of the magnetic survey to the epoch 2010.5

open access: yesAnnals of Geophysics, 2013
A recent stage of the magnetic surveying activities in the Czech Republic was started in the fifties by setting up a basic network of the first order. It consists of 199 points.
Pavel Hejda   +2 more
doaj   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner   +14 more
wiley   +1 more source

The influence of regularization on the geomagnetic core field modeling

open access: yes地球与行星物理论评
Earth's magnetic field is generated through the dynamo action in the liquid outer core. Using observational data from geomagnetic satellites and observatories, we can construct geomagnetic models that describe spatial and temporal variations of the core ...
Juyuan Xu, Yufeng Lin, Keke Zhang
doaj   +1 more source

Cancer‐associated mutations in endometriosis reframe a benign disease through molecular oncology

open access: yesMolecular Oncology, EarlyView.
This review aims to comprehensively analyse cancer‐associated somatic mutations (CAMs) present in endometriotic lesions, emphasizing their biological roles, spatial distribution and implications for translational applications in medicine. By contextualizing a benign state within a genomic framework, this analysis seeks to establish its value as a ...
Clarissa Mujacic   +15 more
wiley   +1 more source

Elements of a Theory of Religious-Secular Competition

open access: yesPolítica & Sociedade, 2017
This article presents basic elements of a theory of religious-secular competition on the individual level. The theory claims that individuals in many societies may choose between religious and secular options, creating a situation of competition between
Jörg Stolz, Pascal Tanner
doaj   +1 more source

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

open access: yesMolecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault   +12 more
wiley   +1 more source

Spatial heterogeneity of hotspot mutations and clonal relatedness in ovarian endometrioid carcinoma

open access: yesMolecular Oncology, EarlyView.
Spatially resolved analysis revealed heterogeneous distributions of selected cancer‐associated mutations within ovarian endometrioid carcinomas. Shared mutations between paired endometrial and ovarian tumors supported clonal relatedness. These findings highlight the value of sampling multiple tumor regions when interpreting molecular profiles ...
Takahito Ashihara   +10 more
wiley   +1 more source

The 1990.0 magnetic repeat station survey and normal reference fields for Italy

open access: yesAnnals of Geophysics, 1994
A survey of 116 repeat stations of the Italian Magnetic Network was carried out between 1989 and 1992. We describe the characteristics of the selected network repeat station sites, the characteristics of the measuring equipment, the data reduction ...
G. Dominici   +3 more
doaj   +1 more source

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