Results 51 to 60 of about 4,663,317 (279)
JMIR Formative Research, 2022 BackgroundAcute stroke care demands fast procedures performed through the collaboration of multiple professionals across multiple organizations.
Marcela Tuler de Oliveira +4 more
doaj +1 more source
Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research
FEBS Letters, EarlyView.What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley +1 more source
Intervention Methods in Secure Care: What Is Going on for Society’s Most Vulnerable Children?
Social SciencesSecure care is used for the most vulnerable and high-risk children in society; however, there is insufficient research examining the way intervention methods are used in this context.
Gavin Heron, Ross Gibson
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Scottish Journal of Residential Child Care, 2022 For children and young people living in residential and secure care, there are links between the relationships they have with Child and Youth Care Workers and positive outcomes.
Amanda Ferguson
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Forensic mental health services as a risk escalator: a case study of ideals and practice [PDF]
, 2004 Medium/low secure units occupy a central role in forensic mental health care, bridging high secure and community services. Although outcomes, assessed in terms of readmission and identified reoffending, have been evaluated, little research exploring ...
Heyman, Bob +9 more
core +1 more source
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Journal of Clinical and Translational Science, 2019 OBJECTIVES/SPECIFIC AIMS: To identify areas of variation in primary care clinician responses to secure messaging and to assess the quality of secure messages by clinicians.
Joy Li-Yueh Lee +2 more
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Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
The outcomes of secure care in Scotland
Scottish Journal of Residential Child Care, 2008 This paper describes the findings of a three year study (November 2002 – 2005) aimed at developing an understanding of the use and effectiveness of secure accommodation in Scotland (Walker et al. 2006).
Andrew Kendrick +6 more
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