Results 1 to 10 of about 497 (135)

Effects of Securigera securidaca (L.) Degen & Dorfl seed extract combined with glibenclamide on paraoxonase1 activity, lipid profile and peroxidation, and cardiovascular risk indices in diabetic rats [PDF]

BioImpacts, 2020
Introduction: Seeds of Securigera securidaca (L.) Degen & Dorfl are rich in flavonoids and phenolic acids which have potent biological effects. The current study was undertaken to evaluate the effects of hydroalcoholic extract of S.
Shahin Alizadeh-Fanalou, Ali Nazarizadeh, Mohammad Babaei, Mohsen Khosravi, Navid Farahmandian, Elham Bahreini   +5 more
doaj   +5 more sources

Evaluation of testicular glycogen storage, FGF21 and LDH expression and physiological parameters of sperm in hyperglycemic rats treated with hydroalcoholic extract of Securigera Securidaca seeds, and Glibenclamide [PDF]

Reproductive Biology and Endocrinology, 2021
Structural and physiological changes in sperm and semen parameters reduce fertility in diabetic patients. Securigera Securidaca (S. Securidaca) seed is a herbal medicine with hypoglycemic, antioxidant, and anti-hypertensive effects.
Mohammad Babaei, Shahin Alizadeh-Fanalou, Alireza Nourian, Sahar Yarahmadi, Navid Farahmandian, Mohsen Nabi-Afjadi, Iraj Alipourfard, Elham Bahreini   +7 more
doaj   +6 more sources

Effectiveness of Hydroalcoholic Seed Extract of Securigera securidaca on Pancreatic Local Renin-Angiotensin System and Its Alternative Pathway in Streptozotocin-Induced Diabetic Animal Model. [PDF]

Oxid Med Cell Longev, 2023
Background. Available data suggest inhibition of the pancreatic local‐renin‐angiotensin system (RAS) reduces tissue complications of diabetes. The purpose of the present study was to investigate the effect of hydroalcoholic seed extract of Securigera securidaca (S. securidaca) (HESS) on the pancreatic local‐RAS and its alternative pathway.
Khomari F, Kiani B, Alizadeh-Fanalou S, Babaei M, Babaei M, Kalantari-Hesari A, Alipourfard I, Mirzaei F, Yarahmadi S, Bahreini E.   +9 more
europepmc   +4 more sources

Antifungal effect of the effect of Securigera securidaca L. vaginal gel on Candida species [PDF]

Current Medical Mycology, 2019
Background and Purpose: Candida species are opportunistic fungi, capable of causing acute and chronic infections in the gastrointestinal tract, vagina, and oral mucosa, among which Candida albicans is the most important species. The Securigera securidaca
Atefeh Raesi Vanani, Masoud Mahdavinia, Heibatullah Kalantari, Saeed Khoshnood, Maryam Shirani   +4 more
doaj   +3 more sources

Effects of Securigera securidaca Extract on Lipolysis and Adipogenesis in Diabetic Rats. [PDF]

Cholesterol, 2014
Diabetes mellitus is associated with dysregulation of adipose tissue metabolism and increased level of serum lipids. In our previous work we found that Securigera securidaca decreases cholesterol level in blood of diabetic rats. The present study was carried out to further investigate the effects of this plant on lipid metabolism, lipolysis, and ...
Ghorbani A, Moradi Marjaneh R, Rajaei Z, Hadjzadeh MA.   +3 more
europepmc   +4 more sources

The Protective Effects of Securigera securidaca Seed Extract on Liver Injury Induced by Bile Duct Ligation in Rats. [PDF]

Biomed Res Int, 2022
This study is aimed at evaluating the effects of Securigera securidaca (SS) seed extract on cholestatic liver injury induced by bile duct ligation (BDL) in rats. Total polyphenols and flavonoids in SS seed extract were determined using a colorimetric assay, and their components were quantified using HPLC. Rats in four groups underwent BDL at the common
Nasehi Z, Kheiripour N, Taheri MA, Ardjmand A, Jozi F, Aghadavod E, Doustimotlagh AH, Shahaboddin ME.   +7 more
europepmc   +4 more sources

Antihyperglycemic and antihyperlipidemic effects of hydroalcoholic extract of Securigera securidaca seeds in streptozotocin-induced diabetic rats

Advanced Biomedical Research, 2015
Background: Hyperlipidemia is an associated complication of diabetes mellitus. Lowering of serum lipid levels seems to be associated with a decrease in the risk of vascular disease and related complications.
Ziba Rajaei, Mousa-Al-Reza Hadjzadeh, Reyhaneh Moradi, Ahmad Ghorbani, Ahmad Saghebi   +4 more
doaj   +3 more sources

Evaluation of serum pro/anti-angiogenic biomarkers in hyperglycemic rats treated with Securigera securidaca seeds, alone and in combination with Glibenclamide [PDF]

Journal of Cardiovascular and Thoracic Research
Introduction: Herbal medicines are commonly used by many people with diabetes in addition to standard treatment. Plants contain numerous known and unknown compounds that may exacerbate or ameliorate diabetes complications.
Elham Bahreini, Mohammad Babaei, Forogh Mohammadi, Shahin Alizadeh-Fanalou   +3 more
doaj   +3 more sources

Pharmacognostic and Anti-Inflammatory Properties of Securigera securidaca Seeds and Seed Oil [PDF]

Research Journal of Pharmacognosy, 2018
Background and objectives: Although weed plants are considered undesirable in a particular situation, some weed seeds can be a valuable and cheap source of therapeutic natural compounds.
Akram Jamshidzadeh, Ardalan Pasdaran, Reza Heidari, Azadeh Hamedi*   +3 more
doaj   +4 more sources

Enhanced Insulin Secretion Through Upregulation of Transcription Factors by Hydroalcoholic Extract of Securigera securidaca Seeds in Diabetic Animal Model [PDF]

Endocrinology, Diabetes & Metabolism
Aim In previous studies, the researchers observed an increase in insulin secretion in STZ‐treated diabetic rats following treatment with the hydroalcoholic extract of Securigera securidaca (HESS) seeds.
Maryam Hasani, Ebrahim Abbasi‐Oshaghi, Fatemeh Khomari, Bahar Kiani, Fatemeh Mirzaei, Iraj Alipourfard, Iraj Khodadadi, Heydar Tayebinia, Mohammad Babaei, Shahin Alizadeh‐Fanalou, Elham Bahreini   +10 more
doaj   +4 more sources